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Titolo:
FEATURES OF MEMORY ON NOVEL SITUATION AND AVOIDANCE-RESPONSE - EVIDENCE FROM COMPARISONS BETWEEN OPEN-FIELD BEHAVIOR AND STEP-THROUGH TASK
Autore:
PAN SY;
Indirizzi:
BEIJING UNIV TRADIT CHINESE MED & MAT MED,DEPT PHARMACOL BEIJING 100029 PEOPLES R CHINA
Titolo Testata:
Zhongguo yaoli xuebao
fascicolo: 2, volume: 16, anno: 1995,
pagine: 125 - 129
SICI:
0253-9756(1995)16:2<125:FOMONS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOCOMOTOR-ACTIVITY; MUSCARINIC RECEPTORS; MOUSE-BRAIN; CAFFEINE;
Keywords:
ANIMAL BEHAVIOR; AVOIDANCE LEARNING; MEMORY; SCOPOLAMINE; CHLORPROMAZINE; PROMETHAZINE; PICROTOXIN; CAFFEINE; PENTOBARBITAL; PROPRANOLOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
S.Y. Pan, "FEATURES OF MEMORY ON NOVEL SITUATION AND AVOIDANCE-RESPONSE - EVIDENCE FROM COMPARISONS BETWEEN OPEN-FIELD BEHAVIOR AND STEP-THROUGH TASK", Zhongguo yaoli xuebao, 16(2), 1995, pp. 125-129

Abstract

AIM: To study the features of memory on novel situation and avoidanceresponse in mice. METHODS: Open-field activity and step-through latency were used to determine the memory of mice on a new environment and avoidance, respectively. RESULTS: The open-field memory was only observed 24 and 48 h after acquisition session. The avoidance memory still existed 72 and 96 h after training session. On d 1 mice were allowed to remain an open-fiedld and step-through for 0.5, 1, 3 and 5 min. On d2 the retention latencies in 0.5- and 1-min groups were shorter than those in 3- and 5-min groups, while the recall activities in open-field were indifferent between these groups. Scopolamine (1 mg . kg(-1)) injected ip 15 min before the first session inhibited the avoidance response and the adaptation to open-field environment in mice. Chlorpromazine, promethazine, picrotoxin and pentobarbital impaired the avoidance memory, but not impaired the open-field memory. CONCLUSION: These results supported the hypothesis that the adaption of mice on open-fieldwas a short or medium term memory.

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Documento generato il 13/07/20 alle ore 08:05:40