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Titolo:
TRIIODOTHYRONINE REGULATES SOMATOSTATIN GENE-EXPRESSION IN CULTURED FETAL-RAT CEREBROCORTICAL CELLS
Autore:
LORENZO MJ; CACICEDO L; TOLON RM; BALSA JA; SANCHEZFRANCO F;
Indirizzi:
HOSP RAMON Y CAJAL,SERV ENDOCRINOL,CARRETERA COLMENAR KM 9 E-28034 MADRID SPAIN HOSP RAMON Y CAJAL,SERV ENDOCRINOL E-28034 MADRID SPAIN INST SALUD CARLOS 3,CTR NACL INVEST CLIN E-28029 MADRID SPAIN
Titolo Testata:
Peptides
fascicolo: 2, volume: 16, anno: 1995,
pagine: 249 - 253
SICI:
0196-9781(1995)16:2<249:TRSGIC>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
THYROID-HORMONES; BRAIN-CELLS; GROWTH-HORMONE; CORTICAL-CELLS; INVITRO; RELEASE; DISEASE; IMMUNOREACTIVITY; HYBRIDIZATION; SECRETION;
Keywords:
SOMATOSTATIN; THYROID HORMONES; CULTURED FETAL CEREBROCORTICAL CELLS; BRAIN DEVELOPMENT AND SOMATOSTATIN; NEUROPEPTIDE GENES EXPRESSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
M.J. Lorenzo et al., "TRIIODOTHYRONINE REGULATES SOMATOSTATIN GENE-EXPRESSION IN CULTURED FETAL-RAT CEREBROCORTICAL CELLS", Peptides, 16(2), 1995, pp. 249-253

Abstract

The effect of triiodothyronine (T-3) on somatostatin (SS) mRNA levelsin cultured fetal rat cerebrocortical cells was studied. Two different experimental approaches were sought. They differed in the length of time in which cells were deprived of thyroid hormones prior to the addition of exogenous T-3. When the cells were not deprived of thyroid hormones, T-3 caused a dose-related decrease in SS mRNA content at all doses tested. However, when the cells were deprived of T-3 for 24 h, a biphasic effect was observed. These findings suggest that T-3 regulates SS gene expression in fetal cultured cerebrocortical cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 05:44:13