Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
KIDNEY-TRANSPLANTATION IN DIABETIC-PATIENTS USING CYCLOSPORINE - 5-YEAR FOLLOW-UP
Autore:
SHAFFER D; SIMPSON MA; MADRAS PN; SAHYOUN AI; CONWAY PA; DAVIS CP; MONACO AP;
Indirizzi:
NEW ENGLAND DEACONESS HOSP,DIV ORGAN TRANSPLANTAT,1 DEACONESS RD BOSTON MA 02215 HARVARD UNIV,SCH MED BOSTON MA 00000
Titolo Testata:
Archives of surgery
fascicolo: 3, volume: 130, anno: 1995,
pagine: 283 - 288
SICI:
0004-0010(1995)130:3<283:KIDUC->2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
STAGE RENAL-DISEASE; CORONARY-ARTERY DISEASE; DIALYSIS PATIENTS; SURVIVAL; RECIPIENTS; RISK; EXPERIENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
D. Shaffer et al., "KIDNEY-TRANSPLANTATION IN DIABETIC-PATIENTS USING CYCLOSPORINE - 5-YEAR FOLLOW-UP", Archives of surgery, 130(3), 1995, pp. 283-288

Abstract

Objective: To review our center's experience with kidney transplantation in diabetic recipients; specifically, to compare long-term (5-year) patient and graft survival rates between diabetic and nondiabetic recipients overall and according to donor source using cyclosporine-based immunosuppression. Design: A retrospective review of all kidney transplants performed over the 7-year period from 1987 to 1993. Setting: Alarge urban tertiary care referral center with a long history of kidney transplantation and care of the diabetic patient. Patients: All patients receiving a kidney transplant, either alone or simultaneously with a pancreas transplant, were reviewed. Main Outcome Measures: Actuarial patient and graft survival, serum creatinine levels, and causes oflate graft loss. Results: There was no significant difference in actuarial 5-year patient or kidney graft survival between diabetic and nondiabetic recipients overall or when analyzed by donor source. There was no significant difference in mean serum creatinine levels at 5 yearsbetween diabetic and nondiabetic recipients overall or between diabetic and nondiabetic cadaveric recipients. While chronic rejection was the major cause of late graft loss in nondiabetic recipients, death with a functioning graft, principally due to cardiovascular disease, was the major cause of graft loss in diabetic recipients. Conclusions: With cyclosporine-based immunosuppression, diabetic kidney transplant recipients have 5-year patient and graft survival rates and allograft function comparable to nondiabetic recipients. Given the high mortality of diabetic patients receiving dialysis, kidney transplantation is the treatment of choice for end-stage diabetic renal disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 05:54:22