Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EVALUATION OF AGE-SPECIFIC NORMAL RANGES FOR PROSTATE-SPECIFIC ANTIGEN
Autore:
SPEIGHTS VO; BRAWN PN; FOSTER DM; SPIEKERMAN AM; KUHL D; RIGGS MW;
Indirizzi:
SCOTT & WHITE MEM HOSP & CLIN,DEPT PATHOL,2401 S 31ST ST TEMPLE TX 76508 SCOTT & WHITE MEM HOSP & CLIN,DEPT CLIN CHEM TEMPLE TX 76508 SCOTT & WHITE MEM HOSP & CLIN,DEPT BIOSTAT TEMPLE TX 76508 SCOTT SHERWOOD & BINDLEY FDN TEMPLE TX 00000 OLIN E TEAGUE VET CTR TEMPLE TX 00000 TEXAS A&M UNIV,COLL MED,HLTH SCI CTR TEMPLE TX 00000 VET AFFAIRS MED CTR,DEPT PATHOL & LAB MED ANN ARBOR MI 00000
Titolo Testata:
Urology
fascicolo: 3, volume: 45, anno: 1995,
pagine: 454 - 457
SICI:
0090-4295(1995)45:3<454:EOANRF>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
SCREENING-TEST; CANCER; SERUM; PSA; MEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
V.O. Speights et al., "EVALUATION OF AGE-SPECIFIC NORMAL RANGES FOR PROSTATE-SPECIFIC ANTIGEN", Urology, 45(3), 1995, pp. 454-457

Abstract

Objectives. To compare the traditional normal range (TNR) of 0.0 to 4.0 ng/mL for serum prostate-specific antigen (PSA) to age-specific normal ranges (ASNRs). Methods. An autopsy series of completely sectioned, clinically benign prostates from 171 consecutive Caucasian men over the age of 40 years was selected. These patients were divided into those having no prostate cancer at autopsy, prostate cancer less than 1 cc in volume, and prostate cancer at least 1 cc in volume. The PSA values of each group were compared using both the TNR and the ASNR. Results. Twenty-three of 105 (21.9%) patients with no cancer had elevated PSA values by the TNR, whereas only 18 (17.1%) were elevated using the ASNR. Nine of 54 (16.7%) with cancer less than 1 cc were elevated usingthe TNR, and 7 of 54 (13.0%,) using the ASNR. Of 12 patients with cancer at least 1 cc, all had elevated PSA levels using the TNR and 11 (91.7%) were elevated using the ASNR. All discrepancies between the TNR and ASNR occurred in the 60- to 79-year age range. Conclusions. Use ofASNRs appears helpful in increasing the specificity of PSA by eliminating some elevated values in patients in their 60s and 70s.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:14:09