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Titolo:
IN-VITRO SUSCEPTIBILITY OF 545 ISOLATES OF CANDIDA SPP TO 4 ANTIFUNGAL AGENTS
Autore:
ARIAS A; AREVALO MP; ANDREU A; RODRIGUEZ C; SIERRA A;
Indirizzi:
UNIV LA LAGUNA,CATEDRA MED PREVENT & SALUD PUBL E-38071 LA LAGUNA SPAIN HOSP UNIV CANARIAS,MICROBIOL SERV TENERIFE SPAIN
Titolo Testata:
Mycoses
fascicolo: 7-8, volume: 37, anno: 1994,
pagine: 285 - 289
SICI:
0933-7407(1994)37:7-8<285:ISO5IO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMPHOTERICIN-B; INVITRO; IDENTIFICATION; ITRACONAZOLE; LY121019; SENSITIVITY; INFECTIONS; TESTS;
Keywords:
CANDIDA ALBICANS; CANDIDA TROPICALIS; CANDIDA PARAPSILOSIS; CANDIDA GLABRATA; SUSCEPTIBILITY TEST; MICRODILUTION TEST; ANTIFUNGAL AGENTS; AMPHOTERICIN B; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
A. Arias et al., "IN-VITRO SUSCEPTIBILITY OF 545 ISOLATES OF CANDIDA SPP TO 4 ANTIFUNGAL AGENTS", Mycoses, 37(7-8), 1994, pp. 285-289

Abstract

The in vitro susceptibility to amphotericin B, fluconazole, itraconazole and ketoconazole of 545 Candida strains from patients treated at the University Hospital of the Canaries was determined by means of a microdilution test. The distribution of the species was as follows: Candida albicans (342), Candida tropicalis (70), Candida glabrata (68), Candida parapsilosis (65). Of Candida albicans isolates, 8.5% and 7.6% showed resistance to itraconazole and fluconazole respectively. Of C. tropicalis isolates 34.3%, 27.1% and 2.9% were resistant to itraconazole, fluconazole and ketaconazole respectively. For C. glabrata, 10.3% and 4.4% of the isolates under study demonstrated resistance to fluconazole and itraconazole respectively. Only 4.6% and 1.5% of C. parapsilosis isolates demonstrated resistance to fluconazole and itraconazole respectively. C. tropicalis was the most resistant strain and C. parapsilosis the most sensitive. The greatest percentages of resistance in vitro were seen with the triazoles.

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Documento generato il 02/12/20 alle ore 16:25:38