Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE ROLE OF CYTOLOGIC EVALUATION OF PLEURAL FLUID IN THE DIAGNOSIS OFMALIGNANT MESOTHELIOMA
Autore:
RENSHAW AA; DEAN BR; ANTMAN KH; SUGARBAKER DJ; CIBAS ES;
Indirizzi:
BRIGHAM & WOMENS HOSP,DEPT RADIOL,75 FRANCIS ST BOSTON MA 02115 BRIGHAM & WOMENS HOSP,DEPT PATHOL BOSTON MA 02115 BRIGHAM & WOMENS HOSP,DEPT SURG BOSTON MA 02115 HARVARD UNIV,SCH MED BOSTON MA 00000 DANA FARBER CANC INST,SURG SERV BOSTON MA 02115 COLUMBIA UNIV,COLL PHYS & SURG,DEPT MED,SURG SERV NEW YORK NY 00000
Titolo Testata:
Chest
fascicolo: 1, volume: 111, anno: 1997,
pagine: 106 - 109
SICI:
0012-3692(1997)111:1<106:TROCEO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIMODALITY THERAPY; CLINICAL PRESENTATION; NATURAL-HISTORY; DIFFUSE;
Keywords:
ASBESTOS; CLINICAL PRESENTATION; CYTOGENETICS; CYTOLOGY; DIAGNOSIS; MESOTHELIOMA; PLEURAL FLUID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
A.A. Renshaw et al., "THE ROLE OF CYTOLOGIC EVALUATION OF PLEURAL FLUID IN THE DIAGNOSIS OFMALIGNANT MESOTHELIOMA", Chest, 111(1), 1997, pp. 106-109

Abstract

Study objective: Treatment of malignant mesothelioma (MM) at an earlystage results in increased survival. Cytologic examination of pleuraleffusions is one of the first diagnostic techniques attempted in these patients. The objective of this study was to define the role of cytologic examination of pleural fluid in facilitating early diagnosis, Design: The medical records and cytologic slides of patients with pleural MM were reviewed, Setting: Medical records were reviewed from two institutions: a large general hospital and a cancer hospital. Patients: Twenty-nine patients ranging in age from 32 to 81 years (mean, 59 years) met the study criteria, Interventions: All patients had at least one cytologic pleural fluid examination, Measurements and results: The median time from initial symptoms to the diagnosis of MM was 8 weeks for all patients, For patients with a positive or suspicious cytologic result, the median was 4 weeks, and in those with a negative cytologic result, it was 12 weeks, The overall sensitivity of cytologic examination for the diagnosis of MM was 32%, Cytogenetic analysis of pleural fluid had a sensitivity of 56%, and was positive in 1 case in which results of cytologic examination were negative, Patients in whom the timefrom presentation to diagnosis was greater than 1 year all had negative cytologic results followed by long periods without further workup, despite a history of exposure to asbestos, Conclusions: A positive or suspicious cytologic result was associated with a decreased median time to diagnosis. Unfortunately, the sensitivity of cytologic examination for a diagnosis of MM was only 32%, Until better diagnostic techniques are developed, we recommend immediate pleural biopsy in patients inwhom MM is suspected and cytologic evaluation of pleural fluid gives negative results.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:51:51