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Titolo:
INDUCTION OF TERATOCARCINOMA F9 CELL-DIFFERENTIATION WITH CIS-DIAMMINE DICHLOROPLATINUM(II) (CDDP)
Autore:
DOI T; SUMI T; NISHINA Y; KOSAKA M; IWAI SA; SAKUDA M; NISHIMUNE Y;
Indirizzi:
OSAKA UNIV,MICROBIAL DIS RES INST,3-1 YAMADAOKA SUITA OSAKA 565 JAPAN OSAKA UNIV,MICROBIAL DIS RES INST SUITA OSAKA 565 JAPAN OSAKA UNIV,FAC DENT,DEPT ORAL & MAXILLOFACIAL SURG 2 SUITA OSAKA 565 JAPAN
Titolo Testata:
Cancer letters
fascicolo: 1, volume: 88, anno: 1995,
pagine: 81 - 86
SICI:
0304-3835(1995)88:1<81:IOTFCW>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMINOGEN ACTIVATOR PRODUCTION; EMBRYONAL CARCINOMA-CELLS; MESSENGER-RNA; DNA; PLATINUM; INVITRO; CISPLATIN; LINES;
Keywords:
CDDP; DIFFERENTIATION; TERATOCARCINOMA F9 CELL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
T. Doi et al., "INDUCTION OF TERATOCARCINOMA F9 CELL-DIFFERENTIATION WITH CIS-DIAMMINE DICHLOROPLATINUM(II) (CDDP)", Cancer letters, 88(1), 1995, pp. 81-86

Abstract

cis-Diammine dichloroplatinum(II) (CDDP) is the salt of a platinum compound which has been noted to have a wide spectrum of activity against malignant disorders. We have studied the effects of CDDP on embryonal carcinoma F9 cell differentiation. In the presence of this agent in vitro, the cells showed rapid morphological changes, a marked increasein the mRNA expression of various differentiation markers accompaniedby a loss of tumorigenicity. These results indicate that the differentiation of F9 cells is induced with CDDP.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:46:37