Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
FAMILY HISTORY AND THE RISK OF ENDOMETRIAL CANCER
Autore:
PARAZZINI F; LAVECCHIA C; MORONI S; CHATENOUD L; RICCI E;
Indirizzi:
IST RIC FARMACOL MARIO NEGRI,VIA ERITREA 62 I-20157 MILAN ITALY UNIV MILAN,OSTET GINECOL CLIN 1 I-20122 MILAN ITALY UNIV MILAN,IST STAT MED & BIOMETRIA I-20133 MILAN ITALY
Titolo Testata:
International journal of cancer
fascicolo: 4, volume: 59, anno: 1994,
pagine: 460 - 462
SICI:
0020-7136(1994)59:4<460:FHATRO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
POPULATION ATTRIBUTABLE RISK; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
F. Parazzini et al., "FAMILY HISTORY AND THE RISK OF ENDOMETRIAL CANCER", International journal of cancer, 59(4), 1994, pp. 460-462

Abstract

The association between a family history of endometrial, breast and ovarian cancer and the risk of endometrial cancer was analyzed on the basis of data from a case-control study conducted in northern Italy between 1983 and 1993. A total of 726 histologically confirmed endometrial-cancer patients (median age 61) admitted to a network of general andteaching hospitals in the Greater Milan area were interviewed. The controls were 2,123 women (median age 59), admitted for acute, non-neoplastic, non-hormone-related diseases to the same network of hospitals where the cases had been identified, with admission diagnoses unrelatedto any of the known or suspected risk factors for endometrial cancer. Among cases, 37 (5.1%) reported a history of endometrial cancer in first-degree relatives. The corresponding figure among controls was 77 (3.6%). In comparison with women with no family history of endometrial cancer, the odds ratio (OR) of endometrial cancer was 1.5 (95% CI [confidence interval], 1.0-2.3) in women with a history of endometrial cancer in first-degree relatives. No relation emerged between endometrialcancer and a family history of breast or ovarian cancer. These results suggest that a family history of endometrial cancer increases the risk of contracting the same disease. However, the proportion of cases attributable to this factor was small: less than 1% of endometrial cancers in this population were attributable to familiar (and hence potentially genetic) factors. (C) 1994 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:54:21