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Titolo:
BIOLOGICALLY-ACTIVE MOLECULES AND DENIAL TISSUE-REPAIR - A COMPARATIVE REVIEW OF REACTIONARY AND REPARATIVE DENTINOGENESIS WITH THE INDUCTION OF ODONTOBLAST DIFFERENTIATION IN-VITRO
Autore:
LESOT H; SMITH AJ; TZIAFAS D; BEGUEKIRN C; CASSIDY N; RUCH JV;
Indirizzi:
FAC MED STRASBOURG,MED BIOL INST,11 RUE HUMANN F-67085 STRASBOURG FRANCE DENT SCH BIRMINGHAM,DEPT ORAL PATHOL BIRMINGHAM W MIDLANDS ENGLAND DENT SCH,DEPT DENT PATHOL & THERAPEUT GR-54006 THESSALONIKI GREECE
Titolo Testata:
Cells and materials
fascicolo: 3, volume: 4, anno: 1994,
pagine: 199 - 218
SICI:
1051-6794(1994)4:3<199:BMADT->2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH-FACTOR-BETA; EPITHELIAL-MESENCHYMAL INTERACTIONS; DENTIN MATRIX PROTEINS; SMOOTH-MUSCLE CELLS; LATENT TGF-BETA; TOOTH DEVELOPMENT; EXTRACELLULAR-MATRIX; BINDING-PROTEIN; IGF-I; IMMUNOHISTOCHEMICAL LOCALIZATION;
Keywords:
ODONTOBLAST DIFFERENTIATION; POLARIZATION; TRANSFORMING GROWTH FACTOR BETA (TGF-BETA); BONE MORPHOGENETIC PROTEINS (BMP); DENTINOGENESIS; EXTRACELLULAR MATRIX; CELL-MATRIX INTERACTION; GROWTH FACTORS; TRANSCRIPTION FACTORS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
112
Recensione:
Indirizzi per estratti:
Citazione:
H. Lesot et al., "BIOLOGICALLY-ACTIVE MOLECULES AND DENIAL TISSUE-REPAIR - A COMPARATIVE REVIEW OF REACTIONARY AND REPARATIVE DENTINOGENESIS WITH THE INDUCTION OF ODONTOBLAST DIFFERENTIATION IN-VITRO", Cells and materials, 4(3), 1994, pp. 199-218

Abstract

Complementary approaches are currently being used to develop active biomaterials for clinical applications in dental tissue repair to promote reactionary and reparative dentinogenesis. Biologically active molecules including growth factors, either alone or in combination with carriers (matrix molecules or inorganic components) have been used to stimulate the metabolism of differentiated odontoblasts and to induce the differentiation of odontoblast-like cells. This paper critically reviews recent data in this area and discusses the mechanisms involved inthe reactionary and reparative processes and during the induction of odontoblast differentiation in vitro. When trying to compare primary and reparative dentinogenesis, two parameters, independently of the molecular basis of the induction, appeared to be of major importance: they concern the regulation in time and space of both the induction and the competence of the target cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 02:54:31