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Titolo:
MATERNAL PLASMA-CONCENTRATIONS OF INSULIN-LIKE GROWTH-FACTOR BINDING PROTEIN-1 AND PLACENTAL PROTEIN-14 IN MULTIFETAL PREGNANCIES BEFORE AND AFTER FETAL REDUCTION
Autore:
ABBAS A; JOHNSON M; CHARD T; NICOLAIDES KH;
Indirizzi:
UNIV LONDON KINGS COLL HOSP,SCH MED,HARRIS BIRTHRIGHT RES CTR FETAL MED LONDON SE5 8RX ENGLAND UNIV LONDON KINGS COLL HOSP,SCH MED,HARRIS BIRTHRIGHT RES CTR FETAL MED LONDON SE5 8RX ENGLAND CHELSEA & WESTMINSTER HOSP,CHARING CROSS & WESTMINSTER MED SCH,DEPT OBSTET & GYNAECOL LONDON ENGLAND ST BARTHOLOMEWS HOSP,COLL MED,DEPT REPROD ENDOCRINOL LONDON ENGLAND
Titolo Testata:
Human reproduction
fascicolo: 1, volume: 10, anno: 1995,
pagine: 207 - 210
SICI:
0268-1161(1995)10:1<207:MPOIGB>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
CIRCULATING LEVELS; 1ST TRIMESTER;
Keywords:
EMBRYO REDUCTION; MULTIPLE PREGNANCIES; PLASMA IGFBP-1; PLASMA PP14;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
A. Abbas et al., "MATERNAL PLASMA-CONCENTRATIONS OF INSULIN-LIKE GROWTH-FACTOR BINDING PROTEIN-1 AND PLACENTAL PROTEIN-14 IN MULTIFETAL PREGNANCIES BEFORE AND AFTER FETAL REDUCTION", Human reproduction, 10(1), 1995, pp. 207-210

Abstract

The aim of this study was to investigate the changes in maternal plasma insulin-like growth factor binding protein-1 (IGFBP-1) and placental protein 14 (PP14) in multifetal pregnancies before and after embryo reduction. Maternal plasma IGFBP-1 and PP14 were measured serially in three groups of pregnant women at 8-21 weeks gestation. Groups 1 and 2were 12 singleton and 12 twin pregnancies achieved after in-vitro fertilization (IVF). Group 3 comprised 26 women with multifetal pregnancies undergoing embryo reduction to twins. In the IVF pregnancies maternal plasma IGFBP-1 and PP14 increased with gestation to reach a peak at20 and 10 weeks respectively; the mean concentrations in twin pregnancies were significantly higher than in singletons. In multifetal pregnancies the mean plasma concentration of both proteins was similar to that of IVF twin pregnancies before reduction; after reduction, the values fell to less than those of twins. These findings suggest that the maximum secretory capacity of the endometrium is achieved with twin pregnancies, In multifetal pregnancies undergoing iatrogenic reduction to twins, total residual endometrial function was less than in twin conceptions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:24:38