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Titolo:
WATER-INTOXICATION IN A PATIENT WITH THE PRADER-WILLI-SYNDROME TREATED WITH DESMOPRESSIN FOR NOCTURNAL ENURESIS
Autore:
ROBSON WLM; SHASHI V; NAGARAJ S; NORGAARD JP;
Indirizzi:
UNIV S CAROLINA,SCH MED,FAC MED,DEPT PEDIAT GREENVILLE SC 00000 GREENVILLE HOSP SYST,CHILDRENS HOSP GREENVILLE SC 00000 MED CENT PEDIAT ANDERSON SC 00000 UNIV COPENHAGEN HOSP,DEPT PEDIAT SURG,DIV UROL DK-2100 COPENHAGEN DENMARK
Titolo Testata:
The Journal of urology
fascicolo: 2, volume: 157, anno: 1997,
pagine: 646 - 647
SICI:
0022-5347(1997)157:2<646:WIAPWT>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Keywords:
ENURESIS; DESMOPRESSIN; PRADER-WILLI SYNDROME; WATER INTOXICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
W.L.M. Robson et al., "WATER-INTOXICATION IN A PATIENT WITH THE PRADER-WILLI-SYNDROME TREATED WITH DESMOPRESSIN FOR NOCTURNAL ENURESIS", The Journal of urology, 157(2), 1997, pp. 646-647

Abstract

Purpose: We report on a girl with the Prader-Willi syndrome who received desmopressin for nocturnal enuresis, and water intoxication developed after she ingested a large amount of fluid. Materials and Methods:The patient received 10 mg. desmopressin at bedtime for enuresis. Shewas hospitalized when a major motor seizure and coma (Glasgow coma scale 8) occurred after ingesting 48 ounces of fluid. Treatment included3% saline, followed by 5% dextrose in water and sodium chloride givenintravenously. Results: Serum sodium increased to 128 mEq./l. and serum glucose remained normal. Computerized tomography and magnetic resonance imaging of the head were normal and revealed no evidence of cerebral pontine myelinosis. Patient consciousness returned to normal by day 5 after the seizure. Conclusions: In patients treated with desmopressin the risk of a seizure or altered level of consciousness can be minimized by not ingesting large quantities of fluid. We recommend that patients drink no more than 8 ounces of fluid on any evening that desmopressin is administered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 05:17:02