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Titolo:
MODELING BRAIN ADAPTATION TO FOCAL DAMAGE
Autore:
GOODALL S; REGGIA JA; CHO SZ;
Indirizzi:
UNIV MARYLAND,DEPT COMP SCI COLLEGE PK MD 20742 POHANG INST SCI & TECHNOL,DEPT COMP SCI & ENGN POHANG 790784 SOUTH KOREA UNIV MARYLAND,DEPT NEUROL COLLEGE PK MD 20742
Titolo Testata:
Journal of the American Medical Informatics Association
, , anno: 1994, supplemento:, S
pagine: 860 - 864
SICI:
1067-5027(1994):<860:MBATFD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
SIMULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
S. Goodall et al., "MODELING BRAIN ADAPTATION TO FOCAL DAMAGE", Journal of the American Medical Informatics Association, 1994, pp. 860-864

Abstract

Determining how feature maps in the cerebral cortex adapt to sudden, focal damage is important for gaining a deeper understanding of neurological illnesses such as stroke. In this paper we describe a neural model of the region of primary sensory cortex related to upper extremityproprioception, and show how the feature map there reorganizes following a simulated lesion. A perilesion zone with decreased activity appears and then gradually expands with time. These results differ from those seen with previous models of cortical lesions, and offer an alternative mechanism to the ''ischemic penumbra'' seen in certain types of stroke.

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Documento generato il 08/04/20 alle ore 09:11:43