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Titolo:
CYTOLOGICAL VS MICROHISTOLOGICAL DIAGNOSIS OF HEPATOCELLULAR-CARCINOMA - COMPARATIVE ACCURACIES IN THE SAME FINE-NEEDLE BIOPSY SPECIMEN
Autore:
CATURELLI E; BISCEGLIA M; FUSILLI S; SQUILLANTE MM; CASTELVETERE M; SIENA DA;
Indirizzi:
CASA SOLLIEVO SOFFERENZA IRCCS,DIV GASTROENTEROL,VIALE CAPPUCCINI I-71013 SAN GIOVANNI ROTO FOGGIA ITALY CASA SOLLIEVO SOFFERENZA IRCCS,SERV ANAT & ISTOL PATOL I-71013 SAN GIOVANNI ROTO FOGGIA ITALY
Titolo Testata:
Digestive diseases and sciences
fascicolo: 12, volume: 41, anno: 1996,
pagine: 2326 - 2331
SICI:
0163-2116(1996)41:12<2326:CVMDOH>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL LIVER-LESIONS; ADENOMATOUS HYPERPLASIA; FEATURES; NODULE;
Keywords:
HEPATOCELLULAR CARCINOMA; LIVER BIOPSY; LIVER DISEASE; DIAGNOSIS; LIVER CIRRHOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
E. Caturelli et al., "CYTOLOGICAL VS MICROHISTOLOGICAL DIAGNOSIS OF HEPATOCELLULAR-CARCINOMA - COMPARATIVE ACCURACIES IN THE SAME FINE-NEEDLE BIOPSY SPECIMEN", Digestive diseases and sciences, 41(12), 1996, pp. 2326-2331

Abstract

There is still debate over the relative merits of cytology and histology in diagnosing hepatocellular carcinoma in cirrhotic livers. Previous comparisons of the diagnostic accuracies of these two methods may have been biased by sampling errors due to multiple punctures. We compared the diagnostic accuracies of cytology and microhistology using tissue and cells from the same point in liver nodules subsequently provedto be hepatocellular carcinoma. A single ultrasound-guided liver-nodule biopsy was obtained with a 20- to 21-G cutting needle from 131 cirrhotic patients. The solid portion of samples was used for microhistology; the remainder was subjected to smear cytology. The results of eachtype of examination were expressed as true positive, nonspecific malignancy, false negative, or inadequate for diagnosis. No false-positivediagnoses were made in 13 benign lesions. In 118 HCC nodules (particularly those < 30 mm in diameter), cytology provided a significantly higher percentage of correct diagnoses (85.6%) that was only slightly inferior to that based on results of both studies (89.8%). The single-biopsy technique generally provides adequate tissue for histology and cytology specimens with a high cellularity. It reduces both the cost andthe risks of fine-needle biopsy diagnosis of hepatocellular carcinoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 12:10:32