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Titolo:
CONCURRENCE OF ALZHEIMERS-DISEASE, PARKINSONS-DISEASE, DIFFUSE LEWY BODY DISEASE, AND AMYOTROPHIC-LATERAL-SCLEROSIS
Autore:
HEDERA P; LERNER AJ; CASTELLANI R; FRIEDLAND RP;
Indirizzi:
CASE WESTERN RESERVE UNIV,DEPT NEUROL,NEUROGENET LAB,2024 ABINGTON RDCLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DEPT NEUROL,NEUROGENET LAB CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,UNIV HOSP CLEVELAND,ALZHEIMER CTR,DEPT NEUROL CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DIV NEUROPATHOL CLEVELAND OH 44106
Titolo Testata:
Journal of the neurological sciences
fascicolo: 2, volume: 128, anno: 1995,
pagine: 219 - 224
SICI:
0022-510X(1995)128:2<219:COAPDL>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOTOR-NEURON DISEASE; ELECTRON-MICROSCOPIC IMMUNOCYTOCHEMISTRY; FRONTAL-LOBE TYPE; INTRANEURONAL INCLUSIONS; PROGRESSIVE DEMENTIA; CLINICAL-FEATURES; UBIQUITIN; DEGENERATION; HIPPOCAMPAL; ASSOCIATION;
Keywords:
ALZHEIMERS DISEASE; PARKINSONS DISEASE; DIFFUSE LEWY BODY DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; UBIQUITIN; DEMENTIA;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
49
Recensione:
Indirizzi per estratti:
Citazione:
P. Hedera et al., "CONCURRENCE OF ALZHEIMERS-DISEASE, PARKINSONS-DISEASE, DIFFUSE LEWY BODY DISEASE, AND AMYOTROPHIC-LATERAL-SCLEROSIS", Journal of the neurological sciences, 128(2), 1995, pp. 219-224

Abstract

A 71-year-old man developed signs of progressive dementia, followed by extrapyramidal and motor neuron disease symptoms, which led to deathin 6 years. Neuropathological examination revealed neuritic plaques, neurofibrillary tangles, and Lewy bodies in the substantia nigra and neocortex. Atrophy and gliosis with intraneuronal ubiquitin inclusions were present in the anterior horns of the spinal cord. Overlapping of Alzheimer's disease, Parkinson's disease, diffuse Lewy body disease and amyotrophic lateral sclerosis is rare and can increase our understanding of the process of neurodegeneration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:43:49