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Titolo:
NITROUS-OXIDE DEPRESSES THE H-REFLEX IN CHILDREN WITH CEREBRAL-PALSY
Autore:
SORIANO SG; LOGIGIAN EL; SCOTT RM; PRAHL PA; MADSEN JR;
Indirizzi:
CHILDRENS HOSP,DEPT ANESTHESIA,300 LONGWOOD AVE BOSTON MA 02115 CHILDRENS HOSP,DEPT NEUROSURG BOSTON MA 02115 HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT NEUROL BOSTON MA 02115
Titolo Testata:
Anesthesia and analgesia
fascicolo: 2, volume: 80, anno: 1995,
pagine: 239 - 241
SICI:
0003-2999(1995)80:2<239:NDTHIC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELECTIVE DORSAL RHIZOTOMY; MUSCLE RIGIDITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
S.G. Soriano et al., "NITROUS-OXIDE DEPRESSES THE H-REFLEX IN CHILDREN WITH CEREBRAL-PALSY", Anesthesia and analgesia, 80(2), 1995, pp. 239-241

Abstract

Hoffmann's reflex or H-reflex (HR) is an electrically elicited reflexthat measures excitability of motoneurons and shares some physiologicproperties with the deep tendon reflex. Children with tendon hyperreflexia due to cerebral palsy usually have higher amplitude HRs. Nitrousoxide (N2O) depresses the HR in patients with normal spinal reflexes,although the effect of N2O in conditions with hyperreflexia such as cerebral palsy is not known. We propose to determine the effect of N2O on the amplitude of the HR under general anesthesia in children with hyperreflexia due to cerebral palsy. We studied eight children undergoing selective dorsal rhizotomy (SDR) for the relief of spasticity. The maximum amplitudes of the HR (HR(max)) and direct motor response (MR(max)) were routinely evoked under the following anesthetic conditions: 1) sufentanil and 66% N2O/33% oxygen; and 2) sufentanil and 100% oxygen. The HR(max) amplitude was significantly lower when N2O was part of the inspired gas mixture. The differences between the no N2O and the 66% N2O groups were significant. The MR(max) did not change significantly. Abnormal spinal reflexes seen in spastic diplegia can be abolishedby inhaled N2O. This finding also suggests that N2O-induced depression of spinal reflexes should be a consideration during physiologic monitoring of the spinal cord under general anesthesia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:06:58