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Titolo:
REDUCED VITAL CAPACITY IN ELDERLY PERSONS WITH HYPERTENSION, CORONARY-HEART-DISEASE, OR LEFT-VENTRICULAR HYPERTROPHY - THE CARDIOVASCULAR HEALTH STUDY
Autore:
ENRIGHT PL; KRONMAL RA; SMITH VE; GARDIN JM; SCHENKER MB; MANOLIO TA;
Indirizzi:
CHS COODINATING CTR,1501 4TH AVE,SUITE 2025 SEATTLE WA 98101 CHS COODINATING CTR SEATTLE WA 98101
Titolo Testata:
Chest
fascicolo: 1, volume: 107, anno: 1995,
pagine: 28 - 35
SICI:
0012-3692(1995)107:1<28:RVCIEP>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY-FUNCTION; LUNG-FUNCTION; MORTALITY; POPULATION; PRESSURE; SYMPTOMS; FAILURE; OLDER; WOMEN; RISK;
Keywords:
CONGESTIVE HEART FAILURE; ECHOCARDIOGRAPHY; HEART-LUNG INTERACTIONS; LEFT VENTRICULAR MASS; PULMONARY FUNCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
P.L. Enright et al., "REDUCED VITAL CAPACITY IN ELDERLY PERSONS WITH HYPERTENSION, CORONARY-HEART-DISEASE, OR LEFT-VENTRICULAR HYPERTROPHY - THE CARDIOVASCULAR HEALTH STUDY", Chest, 107(1), 1995, pp. 28-35

Abstract

The Cardiovascular Health Study provided the opportunity to determinethe association of subclinical and clinical cardiovascular disease with pulmonary function in a population sample of elderly adults. Included were 2,955 women and 2,246 men over age 64 years who were recruitedfor this observational study from four communities and completed extensive examinations that included spirometry, echocardiograms, and blood pressure. Current smokers, past smokers with >20 pack-years of smoking, and persons with a history of asthma, chronic bronchitis, or emphysema were excluded from this analysis, leaving 2,784 (55%) of the cohort. Systolic hypertension or coronary artery disease was associated with 40- to 100-mL decrements in FEV(1) and 50- to 150-mL decrements in FVC, while a history of congestive heart failure was associated with 200 to 300 mL lower FEV(1) and FVC values (p<0.0001), after correcting for age, height, and waist size. Higher left ventricular (LV) mass wasalso significantly associated with a decrease in FEV(1) and FVC in multivariate models. This relationship was strongest with the end-diastolic LV posterior wall thickness component of LV mass. In summary, FEV(1) and FVC are reduced in elderly persons with hypertension, ischemic heart disease, higher LV mass, and congestive heart failure, though the magnitude of these associations is relatively small unless heart failure supervenes. Substantial decrements in percent predicted FEV(1) and FVC should not be attributed to the presence of uncomplicated ischemic heart disease or hypertension alone.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:58:11