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Titolo:
PROPAGATION OF INTERICTAL EPILEPTIC ACTIVITY IN TEMPORAL-LOBE EPILEPSY
Autore:
BAUMGARTNER C; LINDINGER G; EBNER A; AULL S; SERLES W; OLBRICH A; LURGER S; CZECH T; BURGESS R; LUDERS H;
Indirizzi:
UNIV VIENNA,NEUROL CLIN,WAHRINGER GURTEL 18-20 A-1090 VIENNA AUSTRIA CLEVELAND CLIN FDN,DEPT NEUROL CLEVELAND OH 44195 UNIV VIENNA,NEUROSURG CLIN VIENNA AUSTRIA EPILEPSIEZENTRUM BETHEL BIELEFELD GERMANY
Titolo Testata:
Neurology
fascicolo: 1, volume: 45, anno: 1995,
pagine: 118 - 122
SICI:
0028-3878(1995)45:1<118:POIEAI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPHENOIDAL ELECTRODES; DEPTH; ELECTROENCEPHALOGRAPHY; CONNECTIONS; STIMULATION; COMPLEX; FOCI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
C. Baumgartner et al., "PROPAGATION OF INTERICTAL EPILEPTIC ACTIVITY IN TEMPORAL-LOBE EPILEPSY", Neurology, 45(1), 1995, pp. 118-122

Abstract

We recorded interictal spikes with closely spaced scalp electrodes and sphenoidal electrodes in four patients with temporal lobe epilepsy. We used multiple dipole modeling to study the number, three-dimensional intracerebral location, time activity, and functional relationship of the neuronal sources underlying the epileptic spike complexes. In all patients, we found two significant sources generating the interictalspikes which showed considerable overlap in both space and time. Source 1 was located in the mesiobasal temporal lobe and generated a restricted negativity at the ipsilateral sphenoidal electrode and a widespread positivity over the vertex. Source 2 could be attributed to the lateral temporal neocortex and was associated with a relatively restricted negativity at the ipsilateral temporal electrodes and a more widespread positivity over the contralateral hemisphere. The sources were well separated in space, with an average distance of 45 mm between them. The time activities of both sources showed similar biphasic patterns,with the mesial source leading the lateral source by approximately 40msec, suggesting propagation of interictal epileptic activity from the mesiobasal to the lateral temporal lobe.

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Documento generato il 17/09/19 alle ore 23:03:21