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Titolo:
GASTROINTESTINAL DYSFUNCTION IN PARKINSONS-DISEASE DETECTED BY ELECTROGASTROENTEROGRAPHY
Autore:
KANEOKE Y; KOIKE Y; SAKURAI N; WASHIMI Y; HIRAYAMA M; HOSHIYAMA M; TAKAHASHI A;
Indirizzi:
EMORY UNIV,SCH MED,DEPT NEUROL,WOODRUFF MEM BLDG,SUITE 6000,PO DRAWER5 ATLANTA GA 30322 NAGOYA UNIV,SCH MED,DEPT NEUROL NAGOYA AICHI 466 JAPAN
Titolo Testata:
Journal of the autonomic nervous system
fascicolo: 3, volume: 50, anno: 1995,
pagine: 275 - 281
SICI:
0165-1838(1995)50:3<275:GDIPDB>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
NERVOUS-SYSTEM; VAGOTOMY; ORIGIN; SPREAD;
Keywords:
AUTONOMIC NERVOUS SYSTEM; ELECTROGASTROGRAPHY; ELECTROGASTROENTEROGRAPHY; GASTROINTESTINAL DYSFUNCTION; PARKINSONS DISEASE; VAGAL NERVE FUNCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
Y. Kaneoke et al., "GASTROINTESTINAL DYSFUNCTION IN PARKINSONS-DISEASE DETECTED BY ELECTROGASTROENTEROGRAPHY", Journal of the autonomic nervous system, 50(3), 1995, pp. 275-281

Abstract

Electrogastroenterography (EGEG) is a method to record electrical activities of the stomach and the intestine using skin electrodes. We investigated whether this method could be used to detect gastrointestinaldysfunction in patients with idiopathic Parkinson's disease. EGEG recordings were done with ten patients with idiopathic Parkinson's disease and ten control subjects before and after a meal. The patients showed changes in EGEG that were markedly similar to those of acute stage of vagotomized patients reported previously. Patients' increase rate inamplitude of gastric activity after the meal (median: 1.19) was significantly (P < 0.05, Mann-Whitney test) smaller than that of the controls (median: 2.84), and normal temporal frequency decrease of gastric activity after the meal was not seen in the patient group. These results suggest vagal nerve dysfunction of patients with Parkinson's disease, though other possibilities could not be denied. EGEG may be useful to assess patients' gastrointestinal dysfunction though we need furtherstudy to elucidate the relation between pathophysiology of their symptoms and EGEG findings.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:46:55