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Titolo:
HYDROGEN BACKGROUND IN TOTAL-BODY NITROGEN ESTIMATIONS
Autore:
HUMPHRIES IRJ; ALLEN BJ; BLAGOJEVIC N; GASKIN KJ;
Indirizzi:
CHILDRENS HOSP,JAMES FAIRFAX INST PAEDIAT CLIN NUTR,BRIDGE RD CAMPERDOWN NSW AUSTRALIA ST GEORGE CANC CARE CTR KOGARAH NSW AUSTRALIA AUSTRALIAN NUCL SCI & TECHNOL ORG SUTHERLAND NSW AUSTRALIA
Titolo Testata:
Physics in medicine and biology
fascicolo: 1, volume: 40, anno: 1995,
pagine: 201 - 207
SICI:
0031-9155(1995)40:1<201:HBITNE>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACTIVATION ANALYSIS FACILITY; CRITICALLY ILL; INVIVO; CALIBRATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
I.R.J. Humphries et al., "HYDROGEN BACKGROUND IN TOTAL-BODY NITROGEN ESTIMATIONS", Physics in medicine and biology, 40(1), 1995, pp. 201-207

Abstract

Total body nitrogen (TBN) is measured by in vivo prompt gamma neutroncapture analysis. Usually the background under the nitrogen peak is subtracted before calculating TEN from the ratio of nitrogen counts (at10.8 MeV) to hydrogen counts (at 2.2 MeV). The hydrogen acts as an internal standard. The background under the hydrogen peak is usually ignored. The current study was undertaken to measure the variation of thehydrogen background (HB) in patients of different sizes and to determine whether the accuracy of TBN measurements is improved when an HB correction is incorporated. Heavy-water (D2O) phantoms were used to quantify patient HB. D2O simulates patient neutron scattering without contributing to the hydrogen peak. Equations were developed to predict HB in patient measurements. HB was found to vary from 9% of total counts for a 99 kg subject to 19% for a 7 kg infant. It was demonstrated thatthe accuracy of TBN measurements is improved for child-sized anthropometric phantoms of known composition when an HB correction is incorporated.

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Documento generato il 27/11/20 alle ore 02:26:12