Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
TRANSDERMAL HORMONE REPLACEMENT THERAPY AND SKIN IN POSTMENOPAUSAL WOMEN - A PLACEBO-CONTROLLED STUDY
Autore:
MESCHIA M; BRUSCHI F; AMICARELLI F; BARBACINI P; MONZA GC; CROSIGNANI PG;
Indirizzi:
UNIV MILAN,OSTET & GINECOL CLIN 1A,VIA DELLA COMMENDA 12 I-20100 MILAN ITALY CIBA GEIGY CORP,DEPT MED ORIGGIO VARESE ITALY
Titolo Testata:
Menopause
fascicolo: 2, volume: 1, anno: 1994,
pagine: 79 - 82
SICI:
1072-3714(1994)1:2<79:THRTAS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLLAGEN CHANGES; MENOPAUSE;
Keywords:
HORMONE REPLACEMENT THERAPY; SKIN THICKNESS; TRANSDERMAL THERAPEUTIC SYSTEM; PLACEBO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
M. Meschia et al., "TRANSDERMAL HORMONE REPLACEMENT THERAPY AND SKIN IN POSTMENOPAUSAL WOMEN - A PLACEBO-CONTROLLED STUDY", Menopause, 1(2), 1994, pp. 79-82

Abstract

It has been shown that skin collagen decreases in the years after menopause and that oral estrogen replacement therapy is effective in preventing the loss of skin collagen content. Skin thickness, measured radiologically, is a cheap, noninvasive measure of skin collagen content. We explored the effect of a transdermal therapeutic system delivering50 mu g/day of 17 beta-estradiol plus sequential medroxyprogesterone acetate 10 mg, in comparison with placebo, on skin thickness after chronic administration to postmenopausal women. Forty postmenopausal women were randomly treated with transdermal estrogen or with placebo. Treated patients showed a statistically significant increase in skin thickness after 1 year of study when compared with untreated women. Data confirm the negative effect of menopause on skin and show that transdermal estrogens are as effective as oral estrogens in preventing skin-thickness decrease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 04:41:45