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Titolo:
BASAL GANGLIA PHOSPHORUS-METABOLISM IN CHRONIC-SCHIZOPHRENIA
Autore:
DEICKEN RF; CALABRESE G; MERRIN EL; FEIN G; WEINER MW;
Indirizzi:
VET AFFAIRS MED CTR,PSYCHIAT SERV,116-N,4150 CLEMENT ST SAN FRANCISCOCA 94121 DEPT VET AFFAIRS MED CTR,MAGNET RESONANCE UNIT SAN FRANCISCO CA 00000 UNIV CALIF SAN FRANCISCO,DEPT RADIOL SAN FRANCISCO CA 94143 UNIV CALIF SAN FRANCISCO,DEPT MED SAN FRANCISCO CA 94143 UNIV CALIF SAN FRANCISCO,DEPT PSYCHIAT SAN FRANCISCO CA 94143
Titolo Testata:
The American journal of psychiatry
fascicolo: 1, volume: 152, anno: 1995,
pagine: 126 - 129
SICI:
0002-953X(1995)152:1<126:BGPIC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; CEREBRAL GLUCOSE-METABOLISM; TEMPORAL LOBES; BRAIN; NEUROLEPTICS; CORTEX;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
R.F. Deicken et al., "BASAL GANGLIA PHOSPHORUS-METABOLISM IN CHRONIC-SCHIZOPHRENIA", The American journal of psychiatry, 152(1), 1995, pp. 126-129

Abstract

Objective: The authors examined whether there are abnormalities in high-energy phosphorous metabolism in the basal ganglia of schizophrenicpatients. Method: In vivo P-31 magnetic resonance spectroscopic imaging was performed on 18 chronic schizophrenic patients and 16 healthy comparison subjects. The percentages of total phosphorous signal for phosphomonoesters, inorganic phosphate, phosphodiesters, phosphocreatine, and beta-ATP were calculated. Results: The mean percentages of beta-ATP signal in the right and left basal ganglia were significantly lower for the schizophrenic patients than for the comparison group. No other group differences in phosphorous metabolites and no lateral asymmetries in the schizophrenic group were noted. Conclusions: This preliminary study provides support for abnormal high-energy phosphorous metabolism in the basal ganglia of schizophrenic patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:42:16