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Titolo:
INFLUENCE OF THE POSITIONING ERROR ON 3D CONFORMAL DOSE DISTRIBUTIONSDURING FRACTIONATED RADIOTHERAPY
Autore:
RUDAT V; FLENTJE M; OETZEL D; MENKE M; SCHLEGEL W; WANNENMACHER M;
Indirizzi:
UNIV KLINIKUM HEIDELBERG,STRAHLENTHERAP ABT,RADIOL KLIN,NEUENHEIMER FELD 400 HEIDELBERG GERMANY DEUTSCH KREBSFORSCHUNGSZENTRUM D-69120 HEIDELBERG GERMANY
Titolo Testata:
Radiotherapy and oncology
fascicolo: 1, volume: 33, anno: 1994,
pagine: 56 - 63
SICI:
0167-8140(1994)33:1<56:IOTPEO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIATION-THERAPY; PROSTATE-CANCER; PORTAL IMAGES; IRRADIATION; ALIGNMENT; ACCURACY;
Keywords:
CONFORMAL RADIOTHERAPY; PATIENT POSITIONING ERROR; TUMOR CONTROL PROBABILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
V. Rudat et al., "INFLUENCE OF THE POSITIONING ERROR ON 3D CONFORMAL DOSE DISTRIBUTIONSDURING FRACTIONATED RADIOTHERAPY", Radiotherapy and oncology, 33(1), 1994, pp. 56-63

Abstract

The influence of patient immobilization error on 3D planned conformalradiation therapy in tumors of the thorax and pelvis was studied. Themean positioning error in 43 patients with carcinomas of the thorax and pelvis undergoing 3D conformal radiotherapy (laser supported alignment, no immobilization device) was measured. A total of 194 portal films were superposed with the corresponding simulator radiographs according to anatomic landmarks and using a subtrascope. x-, y- and z-axis deviation was determined within a coordinate system. Using specialized software including Fourier transformation the mean positioning error was employed to recalculate the dose distributions of all cases under the influence of random (Gaussian) immobilization uncertainty. The meantwo-dimensional positioning error using the data from all patients was 5.5 (+/- 3.7) mm. The distribution was Gaussian. Dose volume histograms (DVHs) of each patient with and without consideration of positioning uncertainty were compared on the base of tumor control probability estimations (TCP) using published DVH reduction and TCP algorithms. Inclusion of the positioning error resulted in a mean decrease in TCP (given as the difference between the TCP assuming no positioning error and the TCP modified by the positioning error) of 2% in a series of esophagus carcinomas and of 5% in the prostate carcinomas when looking atgross tumor volume (GTV), only. Planning target volume (PTV) exhibited a relative decrease in TCP of 5% and 11%, respectively.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:45:05