Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EXERCISE GATED PLANAR MYOCARDIAL PERFUSION IMAGING USING TC-99M SESTAMIBI FOR THE DIAGNOSIS OF CORONARY-ARTERY DISEASE - AN ALTERNATIVE TO EXERCISE TOMOGRAPHIC IMAGING
Autore:
JAMAR F; TOPCUOGLU R; CAUWE F; DECOSTER P; ROELANTS V; BECKERS C; WIJNS W; MELIN JA;
Indirizzi:
UNIV CATHOLIQUE LOUVAIN,SCH MED,CTR NUCL MED,UCL 5430,AVE HIPPOCRATE 54 B-1200 BRUSSELS BELGIUM UNIV CATHOLIQUE LOUVAIN,SCH MED,CTR NUCL MED B-1200 BRUSSELS BELGIUM UNIV LOUVAIN,SCH MED,DIV CARDIOL LOUVAIN BELGIUM
Titolo Testata:
European journal of nuclear medicine
fascicolo: 1, volume: 22, anno: 1995,
pagine: 40 - 48
SICI:
0340-6997(1995)22:1<40:EGPMPI>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
METHOXY ISOBUTYL ISONITRILE; EMISSION COMPUTED-TOMOGRAPHY; ISCHEMIC-HEART-DISEASE; TC-99M SESTAMIBI; TL-201; SPECT; SCINTIGRAPHY; 2-METHOXY-ISOBUTYL-ISONITRILE; QUANTIFICATION; QUANTITATION;
Keywords:
MULTI-GATED PLANAR IMAGING; SINGLE-PHOTON EMISSION TOMOGRAPHY; SESTAMIBI; TC-99M; CORONARY ARTERY DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
F. Jamar et al., "EXERCISE GATED PLANAR MYOCARDIAL PERFUSION IMAGING USING TC-99M SESTAMIBI FOR THE DIAGNOSIS OF CORONARY-ARTERY DISEASE - AN ALTERNATIVE TO EXERCISE TOMOGRAPHIC IMAGING", European journal of nuclear medicine, 22(1), 1995, pp. 40-48

Abstract

Single-photon emission tomography (SPET) using technetium-99m labelled myocardial tracers (e.g, Tc-99m-sestamibi) has become one of the most popular myocardial imaging methods for the diagnosis of coronary artery disease (CAD). This prospective study was designed to evaluate thediagnostic performance of Tc-99m-sestamibi exercise gated planar myocardial imaging by comparison with both visual and quantitative analyses of SPET. The study was conducted in 115 consecutive patients with known or suspected CAD, including 54 patients with a previous myocardialinfarction (MI), referred for exercise testing prior to coronary angiography. Multi-gated planar imaging and SPET were performed after bicycle exercise. The end-diastolic (ED) and SPET images were visually scored (SVi). Myocardial uptake was quantitated on SPET slices using maximum count circumferential profiles (SQu) and defect extent was measured by comparison with gender-matched data sets obtained from 27 controls (<5% likelihood of CAD). CAD was defined as coronary artery stenosis>50% and/or regional wall motion abnormality. The cut-off criteria for positivity of the three procedures were determined from receiver operating characteristic (ROC) curves derived from the data of patients without previous MI. The area under the ROC curves was similar for ED, SVi and SQu. This was confirmed by the analysis of sensitivity performed using the ROC curve-derived cut-off criteria, in patients with or without previous MI. SVi was more sensitive than ED in identifying the diseased vessel(s) (ED: 41% vs SVi: 80%; P<0.0005) but ED was more specific in this respect (ED: 79% vs SVi: 61%; P<0.0005). We conclude that visual analysis of ED images obtained from gated Tc-99m-sestamibi stress planar imaging is a valuable alternative to SPET imaging for the diagnosis of CAD. SPET is, however, more accurate for the evaluation of the disease extent and localization and therefore remains the methodof choice for the assessment of myocardial perfusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:21:02