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Titolo:
INVESTIGATION OF THE USE OF X-RAY CT IMAGES FOR ATTENUATION COMPENSATION IN SPECT
Autore:
LACROIX KJ; TSUI BMW; HASEGAWA BH; BROWN JK;
Indirizzi:
UNIV N CAROLINA,DEPT BIOMED ENGN CHAPEL HILL NC 00000 UNIV N CAROLINA,DEPT RADIOL CHAPEL HILL NC 00000 UNIV CALIF SAN FRANCISCO,DEPT RADIOL SAN FRANCISCO CA 00000 UNIV CALIF SAN FRANCISCO,BIOENGN GRAD GRP SAN FRANCISCO CA 00000
Titolo Testata:
IEEE transactions on nuclear science
fascicolo: 6, volume: 41, anno: 1994,
parte:, 2
pagine: 2793 - 2799
SICI:
0018-9499(1994)41:6<2793:IOTUOX>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION; TOMOGRAPHY; TL-201;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
K.J. Lacroix et al., "INVESTIGATION OF THE USE OF X-RAY CT IMAGES FOR ATTENUATION COMPENSATION IN SPECT", IEEE transactions on nuclear science, 41(6), 1994, pp. 2793-2799

Abstract

This study investigates the general use of single-beam Xray computed tomography (CT) images for generating attenuation maps for compensation of photon attenuation in SPECT images. A 3D mathematical thorax phantom is used to simulate both emission and transmission projection datafor monoenergetic (radionuclide) and polyenergetic (X-ray) sources, Polyenergetic transmission projection data are simulated for a standardX-ray spectrum and fan-beam geometry. The projection data are reconstructed using filtered backprojection to form an X-ray CT image which is then scaled to produce an estimate of the attenuation map at the energy of the emission radionuclide. Emission projection data are simulated for a fan-beam geometry at the energies of Tl-201 and Tc-99m, two radionuclides commonly used in cardiac SPECT. Detector response and scatter are not included in the model. Noiseless, emission projection data are iteratively reconstructed using the ML-EM algorithm with nonuniform attenuation compensation and attenuation maps derived from both the simulated X-ray CT image and from a simulated monoenergetic transmission CT image. The attenuation maps generated from the X-ray CT imagesaccurately estimate the attenuation coefficient for muscle and lung tissues, but not for bone tissues, which show error in the attenuation coefficient of 21-42% for spinal bone and 34-58% for rib bone. However, despite the inaccurate estimate of bone attenuation, the reconstructed SPECT images provide estimates of myocardial radioactivity concentration to within 9% and show few artifacts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 01:52:28