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Titolo:
MOLECULAR CHARACTERIZATION OF THE BREAKPOINTS OF AN INVERSION FIXED BETWEEN DROSOPHILA-MELANOGASTER AND D-SUBOBSCURA
Autore:
CIRERA S; MARTINCAMPOS JM; SEGARRA C; AGUADE M;
Indirizzi:
UNIV BARCELONA,FAC BIOL,DEPT GENET,DIAGONAL 645 E-08071 BARCELONA SPAIN UNIV BARCELONA,FAC BIOL,DEPT GENET E-08071 BARCELONA SPAIN
Titolo Testata:
Genetics
fascicolo: 1, volume: 139, anno: 1995,
pagine: 321 - 326
SICI:
0016-6731(1995)139:1<321:MCOTBO>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
RP49 GENE REGION; OBSCURA GROUP; X-CHROMOSOME; NUCLEOTIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
S. Cirera et al., "MOLECULAR CHARACTERIZATION OF THE BREAKPOINTS OF AN INVERSION FIXED BETWEEN DROSOPHILA-MELANOGASTER AND D-SUBOBSCURA", Genetics, 139(1), 1995, pp. 321-326

Abstract

The two breakpoints of a chromosomal inversion fixed since the split of Drosophila melanogaster and D. subobscura lineages have been isolated and sequenced in both species. The regions spanning the breakpointsinitially were identified by the presence of two signals after interspecific in situ hybridization on polytene chromosomes. Interspecific comparison of the sequenced regions allowed us to delineate the location of the breakpoints. Close to one of these breakpoints a new transcription unit (bcn92) has been identified in both species. The inversion fixed between D. melanogaster and D. subobscura does not seem to have broken any transcription unit. Neither complete nor defective transposable elements were found in the regions encompassing the breakpoints. Short thymine-rich sequences (30-50 bp long) have been found borderingthe breakpoint regions. Although alternating Pur-Pyr sequences were detected, these putative target sites for topoisomerase II were not differentially clustered in the breakpoints.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:15:48