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OPAC HELP

Titolo:
PERITONEAL-DIALYSIS PRESCRIPTION - THE CLEARANCE PEAK MODEL
Autore:
VIRGA G; AMICI G; DARIN G;
Indirizzi:
OSPED REG S MARIA BATTUTI,DIV NEFROL & DIALISI I-31100 TREVISO ITALY OSPED REG S MARIA BATTUTI,DIV NEFROL & DIALISI I-31100 TREVISO ITALY OSPED REG S MARIA BATTUTI,INST CLIN CHEM I-31100 TREVISO ITALY
Titolo Testata:
International journal of artificial organs
fascicolo: 10, volume: 17, anno: 1994,
pagine: 537 - 542
SICI:
0391-3988(1994)17:10<537:PP-TCP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAPD;
Keywords:
PERITONEAL DIALYSIS; CREATININE CLEARANCE; ULTRAFILTRATION; DIALYSIS PRESCRIPTION; CLEARANCE PEAK MODEL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
G. Virga et al., "PERITONEAL-DIALYSIS PRESCRIPTION - THE CLEARANCE PEAK MODEL", International journal of artificial organs, 17(10), 1994, pp. 537-542

Abstract

Creatinine clearance (GRCL) was studied in 20 patients on CAPD in relation to the dwell times (DT), in order to establish a personalised dialysis schedule with the best clearance (CL) results, while respectingthe patient's life-style. By calculating the CRCL from the two exchanges with dwell-times of 4 and 8 hours (2 1, 2.27%), curves (2nd degreepolynomial regression) were plotted with three points (0h, 4h, 8h) for CRCL and the ultrafiltration rate (UF) as a function of the DT. The DT corresponding to the CRCL peak (CLPeak-time) was calculated for each subject with the first derivative of the function. On the basis of the CRCL obtained with the three most common DT (4h, 6h, 8h), we divided the patients into three categories (CLPeak;time <5h: ''fast'': 5-7h:''normal''; >7h: ''slow'') for the best CRCL correspondence of the 4h, 6h or 8h exchanges respectively. Also the 8h/4h ratio was used to determine CLPeak-time. For each of the three categories there is a corresponding dialysis schedule for the best CRCL and UF results of the exchanges with DT of 4, 6 and 8 hours, plus the theoretical calculation of the daily CRCL obtainable (''fast'': APD; ''normal''' CAPD 4 exchanges/DAPD 4 exchanges; ''slow'': CAPD 4 exchanges). The ''CLPeak'' dialysis prescription model therefore identifies the most advantageous DT for each patient by using the CRCL values of two 2.27% exchanges of 4 and 8h respectively. Functional classification into three categories may give a rational orientation to dialysis prescription in order to reach the maximum CRCL possible with the individual peritoneal transport rates.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 22:28:47