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Titolo:
ESTABLISHMENT OF CREATININE CLEARANCE REFERENCE VALUES FOR OLDER WOMEN
Autore:
SOKOLL LJ; RUSSELL RM; SADOWSKI JA; MORROW FD;
Indirizzi:
TUFTS UNIV,USDA,HUMAN NUTR RES CTR AGING,711 WASHINGTON ST BOSTON MA 02111
Titolo Testata:
Clinical chemistry
fascicolo: 12, volume: 40, anno: 1994,
pagine: 2276 - 2281
SICI:
0009-9147(1994)40:12<2276:EOCCRV>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLOMERULAR-FILTRATION RATE; SERUM CREATININE; RENAL-FUNCTION; ENZYMATIC METHOD; KIDNEY-FUNCTION; COOKED MEAT; AGE; PARAMETERS; DISEASE; PLASMA;
Keywords:
REFERENCE INTERVAL; SEX- AND AGE-RELATED EFFECTS; GLOMERULAR FILTRATION RATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
L.J. Sokoll et al., "ESTABLISHMENT OF CREATININE CLEARANCE REFERENCE VALUES FOR OLDER WOMEN", Clinical chemistry, 40(12), 1994, pp. 2276-2281

Abstract

Age-adjusted reference ranges for creatinine clearance were determined in 279 women, ages 40-95 years, who were housed in a metabolic research unit and consumed a meat-free diet. Creatinine clearance, but not serum creatinine, declined with age by 0.63 mL/min per 1.73 m(2) per year. Serum and urine creatinine concentrations, used to calculate clearances, were analyzed by a kinetic Jaffe, procedure. In a subset of 100 subjects, fasting serum creatinine values averaged 8.3 +/- 5.2 (SD) mu mol/L higher when measured by the kinetic Jaffe procedure than by an enzymatic method (creatinine PAP). The Cockcroft-Gault formula for estimating creatinine clearance from serum creatinine in women was validated, and the modification factor for the male equation was determined to be 0.84 (95% confidence interval 0.83-0.86) confirming the suggested 15% correction. A prediction formula derived from this population was similar in accuracy to the Cockcroft-Gault formula.

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Documento generato il 15/07/20 alle ore 08:50:03