Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
INCREASED SERUM IRON AND IRON SATURATION WITHOUT LIVER IRON ACCUMULATION DISTINGUISH CHRONIC HEPATITIS-C FROM OTHER CHRONIC LIVER-DISEASES
Autore:
ARBER N; KONIKOFF FM; MOSHKOWITZ M; BARATZ M; HALLAK A; SANTO M; HALPERN Z; WEISS H; GILAT T;
Indirizzi:
TEL AVIV MED CTR & SCH MED,DEPT GASTROENTEROL,6 WEIZMAN ST IL-64249 TEL AVIV ISRAEL ICHILOV HOSP,TEL AVIV MED CTR,DEPT GASTROENTEROL TEL AVIV ISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Digestive diseases and sciences
fascicolo: 12, volume: 39, anno: 1994,
pagine: 2656 - 2659
SICI:
0163-2116(1994)39:12<2656:ISIAIS>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOCHROMATOSIS; STORES; FERRITIN; OVERLOAD;
Keywords:
HEPATITIS; IRON; HEMOCHROMATOSIS; HCV; HBV; CHRONIC LIVER DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
N. Arber et al., "INCREASED SERUM IRON AND IRON SATURATION WITHOUT LIVER IRON ACCUMULATION DISTINGUISH CHRONIC HEPATITIS-C FROM OTHER CHRONIC LIVER-DISEASES", Digestive diseases and sciences, 39(12), 1994, pp. 2656-2659

Abstract

One hundred twenty-three patients with chronic liver diseases of various etiologies were evaluated for their iron status. The patients weredivided into four distinct groups: chronic hepatitis C (63), chronic hepatitis B (14), B + C (3) and nonviral chronic liver diseases (43). In 107 patients (87%) the chronic liver disease was confirmed by biopsy. Mean serum iron (+/-SD) levels in the above four groups were: 166 +/- 62, 103 + 52, 142 +/- 48, and 115 mu g/dl; iron-binding capacity was 346 +/- 80, 325 +/- 72, 297 +/- 27, and 374 +/- 75 mu g/dl, and ironsaturation 50 +/- 18, 32 +/- 16, 48 +/- 16, and 28 +/- 10%, respectively. Serum ferritin, increased in all four groups, was highest in HCV;however, no evidence of hepatic iron accumulation could be found in any of the patients. There were no significant differences in liver function parameters measured in the four groups. We conclude that serum iron, iron saturation, and ferritin are increased in patients with hepatitis C in comparison to hepatitis B or other nonviral, nonhemochromatotic liver diseases. The increased iron status in hepatitis C patientsis not manifested by increased liver iron. Awareness of these distinct features of chronic hepatitis C is essential in the diagnosis and treatment of chronic liver diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 04:00:49