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Titolo:
AMPHOTERICIN-B DERIVATIVE BLOCKS HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ENTRY AFTER CD4 BINDING - EFFECT ON VIRUS-CELL FUSION BUT NOT ON CELL-CELL FUSION
Autore:
PLESKOFF O; SEMAN M; ALIZON M;
Indirizzi:
INST COCHIN GENET MOLEC,INSERM,U332,22 RUE MECHAIN F-75014 PARIS FRANCE INST COCHIN GENET MOLEC,INSERM,U332 F-75014 PARIS FRANCE UNIV DENIS DIDEROT,IMMUNODIFFERENCIAT LAB F-75005 PARIS FRANCE
Titolo Testata:
Journal of virology
fascicolo: 1, volume: 69, anno: 1995,
pagine: 570 - 574
SICI:
0022-538X(1995)69:1<570:ADBHTE>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SULFATED POLYSACCHARIDES; SYNCYTIUM FORMATION; HIV-1 REPLICATION; DEXTRAN SULFATE; INHIBITION; ACTIVATION; INFECTION; HYPERICIN; INVITRO; CHEMOTHERAPY;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
O. Pleskoff et al., "AMPHOTERICIN-B DERIVATIVE BLOCKS HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ENTRY AFTER CD4 BINDING - EFFECT ON VIRUS-CELL FUSION BUT NOT ON CELL-CELL FUSION", Journal of virology, 69(1), 1995, pp. 570-574

Abstract

The antiviral effect of MS8209, an amphotericin B derivative, was studied in CD4(+) cells transfected with a lacZ gene inducible upon humanimmunodeficiency virus type 1 (HIV-1) infection. MS8209 was shown to block virus entry after receptor binding and probably before virus-cell membrane fusion, but it had no effect on syncytium formation, although both processes are mediated by HIV-1 envelope proteins and CD4.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 04:32:58