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Titolo:
THE APPLICABILITY OF ANTIDEPRESSANTS IN THE DEPRESSED MEDICALLY ILL -AN OPEN CLINICAL-TRIAL WITH FLUOXETINE
Autore:
HUYSE FJ; ZWAAN WA; KUPKA R;
Indirizzi:
FREE UNIV AMSTERDAM,DEPT PSYCHIAT C-L,DE BOELELAAN 1117,PO 7057,BOX 1071MB 1007 MC AMSTERDAM NETHERLANDS AMSTERDAM MED CTR,DEPT PSYCHIAT AMSTERDAM NETHERLANDS
Titolo Testata:
Journal of psychosomatic research
fascicolo: 7, volume: 38, anno: 1994,
pagine: 695 - 703
SICI:
0022-3999(1994)38:7<695:TAOAIT>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSULTATION-LIAISON PSYCHIATRY; CONCORDANCE; PHARMACOTHERAPY; PREDICTION; SYMPTOMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
F.J. Huyse et al., "THE APPLICABILITY OF ANTIDEPRESSANTS IN THE DEPRESSED MEDICALLY ILL -AN OPEN CLINICAL-TRIAL WITH FLUOXETINE", Journal of psychosomatic research, 38(7), 1994, pp. 695-703

Abstract

In the literature the side-effects and medical complications of tricyclic antidepressants (TCAs), in the medically ill have been extensively reviewed. This study uses a prospective design to examine these issues' questions in an almost solely in-patient C-L population (N = 37) treated with a serotinergic antidepressant (fluoxetine). A first remarkable finding is the fact that 83% of the patients have complaints comparable with the side-effects of the drug, prior to its administration. Second, although the drop-out rates (DO) are comparable with those inearlier studies, in this study DO do not seem to be related to the seriousness of the side-effects of the drug. The more serious side-effects were hyponatremia (N = 1) and gastrointestinal symptoms (N = 3). Incontrast to TCAs no psychiatric side-effects have to be reported. Therefore this study suggests that with good medical supervision fluoxetine can be used in the treatment of seriously medically ill patients with depressive co-morbidity.

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Documento generato il 07/07/20 alle ore 05:32:05