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Titolo:
CUTANEOUS MELANOMA-ASSOCIATED RETINOPATHY
Autore:
KIM RY; RETSAS S; FITZKE FW; ARDEN GB; BIRD AC;
Indirizzi:
MOORFIELDS EYE HOSP,PROF UNIT,CITY RD LONDON EC1V 2PD ENGLAND MOORFIELDS EYE HOSP,PROF UNIT LONDON EC1V 2PD ENGLAND INST OPHTHALMOL LONDON ENGLAND CHARING CROSS HOSP LONDON ENGLAND
Titolo Testata:
Ophthalmology
fascicolo: 11, volume: 101, anno: 1994,
pagine: 1837 - 1843
SICI:
0161-6420(1994)101:11<1837:CMR>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANCER-ASSOCIATED RETINOPATHY; RETINITIS-PIGMENTOSA; PARANEOPLASTIC RETINOPATHY; MALIGNANT-MELANOMA; NIGHT BLINDNESS; AUTOANTIBODIES; RECOVERIN; PROTEIN; DEFECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
R.Y. Kim et al., "CUTANEOUS MELANOMA-ASSOCIATED RETINOPATHY", Ophthalmology, 101(11), 1994, pp. 1837-1843

Abstract

Purpose: To define further the syndrome of cutaneous melanoma-associated retinopathy, of which only five affected patients have been reported previously. Methods: Three men with melanoma-associated retinopathywere examined and studied electrophysiologically. Two were studied indetail psychophysically. Results: Visual symptoms consisted of flickering black and white spots, shimmering patches of colors, and night blindness. The onset was acute and nonprogressive. Reduced amplitudes were observed in the flash electroretinographic b-wave and the pattern electroretinogram. Color vision, contrast sensitivity, and light- and dark-adapted perimetric sensitivities were abnormal. In one patient, the rate of dark adaptation was normal with elevated final cone and rod thresholds. Conclusions: Melanoma-associated retinopathy is a paraneoplastic syndrome distinct from cancer-associated retinopathy with a different visual prognosis. It may preferentially affect men.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 07:30:07