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Titolo:
NON-DIPPING RELATED TO CARDIOVASCULAR EVENTS IN ESSENTIAL HYPERTENSIVE PATIENTS
Autore:
ZWEIKER R; EBER B; SCHUMACHER M; TOPLAK H; KLEIN W;
Indirizzi:
GRAZ UNIV,DEPT INTERNAL MED,AUENBRUGGERPL 15 A-8036 GRAZ AUSTRIA GRAZ UNIV,DIV CARDIOL A-8036 GRAZ AUSTRIA
Titolo Testata:
Acta medica austriaca
fascicolo: 3, volume: 21, anno: 1994,
pagine: 86 - 89
SICI:
0303-8173(1994)21:3<86:NRTCEI>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR HYPERTROPHY; PRESSURE MONITORING DEVICES; BLOOD-PRESSURE; FRAMINGHAM; DIPPERS; RISK;
Keywords:
ESSENTIAL HYPERTENSION; AMBULATORY BLOOD PRESSURE MONITORING; DIPPERS; NON-DIPPERS; MYOCARDIAL INFARCTION; APOPLEXY; CIRCADIAN BLOOD PRESSURE RHYTHM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
R. Zweiker et al., "NON-DIPPING RELATED TO CARDIOVASCULAR EVENTS IN ESSENTIAL HYPERTENSIVE PATIENTS", Acta medica austriaca, 21(3), 1994, pp. 86-89

Abstract

About 1 third of all patients with essential hypertension reveal an impaired circadian pattern of blood pressure. This phenomenon called ''non-dipping'' (i.e. a lack of the normal noctumal fall in blood pressure) is related to a higher incidence of end-organ damage such as left ventricular hypertrophy. It is the purpose of this study to evaluate, whether or not non-dipping of blood pressure may worsen the prognosis of hypertensive subjects. 116 consecutive hypertensives underwent an ambulatory blood pressure monitoring (ABPM) using the Spacelabs 2000 device. 2 groups were established: Group I (n = 87) were ''dippers'', group II (n = 29) ''non-dippers'' showing a diminished or even lack of nocturnal fall in blood pressure. No difference was seen concerning sex, mean 24-hour systolic blood pressure, systolic and diastolic casual blood pressure and heart rate. However, a significant difference in age and mean 24-hour diastolic blood pressure could be observed. In a follow-up investigation after approximately 31 months all patients and/or their physicians were contacted concerning cardiovascular events during the time since the ABPM was performed. In Group I only 1 transientischemic attack occurred, but in group II 4 patients showed major cardiovascular events: 3 deaths occurred (2 of which caused by myocardialinfarction, 1 by apoplexy), while 1 suffered from a transient ischemic attack (p < 0.001). Thus, in essential hypertension non-dipping of blood pressure is associated with an increased occurrence of cardiovascular events, and, therefore, the circadian blood pressure profile should be carefully monitored.

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Documento generato il 28/11/20 alle ore 21:32:18