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Titolo:
SUPPRESSION OF SPLENIC ENZYME-ACTIVITIES BY ADMINISTRATION OF AMINOPEPTIDASE-N (CD13) INHIBITORS - RELATIONSHIP BETWEEN ACTIONS IN-VIVO ANDIN-VITRO
Autore:
KOCHA T; OHTSUKA E; FUNAHASHI T; FUKUDA T; AOYAGI T;
Indirizzi:
SHOWA COLL PHARMACEUT SCI MACHIDA TOKYO 194 JAPAN INST MICROBIAL CHEM,SHINAGAWA KU TOKYO 141 JAPAN
Titolo Testata:
Journal of enzyme inhibition
fascicolo: 3, volume: 8, anno: 1994,
pagine: 187 - 195
SICI:
8755-5093(1994)8:3<187:SOSEBA>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHYSICOCHEMICAL PROPERTIES; BIOLOGICAL-ACTIVITIES; PURIFICATION; DIFFERENTIATION; KALLIKREIN; TAXONOMY; BESTATIN;
Keywords:
PROBESTIN; ACTINONIN; LEUHISTIN; BESTATIN; AMASTATIN; ARPHAMENINE A; PROTEASES; GLYCOSIDASES; ECTOENZYMES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
T. Kocha et al., "SUPPRESSION OF SPLENIC ENZYME-ACTIVITIES BY ADMINISTRATION OF AMINOPEPTIDASE-N (CD13) INHIBITORS - RELATIONSHIP BETWEEN ACTIONS IN-VIVO ANDIN-VITRO", Journal of enzyme inhibition, 8(3), 1994, pp. 187-195

Abstract

The enzymatic changes in murine spleen caused by the administration for 20 successive days of various inhibitors of aminopeptidase N (leucocyte antigen CD13) have been compared. When compared with the control (saline), most of the inhibitors significantly suppressed splenic enzyme activities including those of ectoenzymes. A multivariate study indicated that the in vivo effects of the inhibitors were closely relatedto their inhibitory actions in vitro.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 18:49:03