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Titolo:
NOUN AND VERB RETRIEVAL BY NORMAL SUBJECTS STUDIES WITH PET
Autore:
WARBURTON E; WISE RJS; PRICE CJ; WEILLER C; HADAR U; RAMSAY S; FRACKOWIAK RSJ;
Indirizzi:
INST NEUROL,DEPT COGNIT NEUROL,QUEEN SQ LONDON WC1N 3BG ENGLAND HAMMERSMITH HOSP,MRC,CTR CLIN SCI,CYCLOTRON UNIT LONDON ENGLAND CHARING CROSS & WESTMINSTER MED SCH,ACAD DEPT NEUROSCI LONDON ENGLAND UNIV KLINIKUM ESSEN,NEUROL KLIN & POLIKLIN D-45122 ESSEN GERMANY TEL AVIV UNIV,DEPT PSYCHOL RAMAT AVIV ISRAEL NUCL MED & ULTRASOUND ASSOCIATES,ASHLEY CTR WESTMEAD NSW AUSTRALIA
Titolo Testata:
Brain
, volume: 119, anno: 1996,
parte:, 1
pagine: 159 - 179
SICI:
0006-8950(1996)119:<159:NAVRBN>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
TEMPORAL LANGUAGE AREA; SLOWLY PROGRESSIVE APHASIA; LEXICAL DECISION TASK; PHYSICAL PERFORMANCE; ALZHEIMERS-DISEASE; WORD-COMPREHENSION; RETRACTABLE SEPTA; SEMANTIC MEMORY; IMAGES; IMPAIRMENT;
Keywords:
PET; WORD RETRIEVAL; VERBS; NOUNS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
92
Recensione:
Indirizzi per estratti:
Citazione:
E. Warburton et al., "NOUN AND VERB RETRIEVAL BY NORMAL SUBJECTS STUDIES WITH PET", Brain, 119, 1996, pp. 159-179

Abstract

PET activation studies identify significant local changes in regionalcerebral blood flow (rCBF) in contrasts of behavioural tasks with control states, and these local changes identify net changes in local synaptic activity. A number of studies on word retrieval have all demonstrated left frontal (dorsolateral and medial) involvement in the task. However, there have been differences in the responses observed in the left temporal lobe, with variously a deactivation (significant decrease in rCBF), no response and an activation (significant increase in rCBF). In the four studies described here, we have examined word (verbs and nouns) retrieval contrasted with a number of different control states. The studies confirmed extensive activation of the left dorsolateral prefrontal cortex and, medially, the anterior cingulate cortex and the supplementary motor area (SMA). Activations of the left posterior temporal lobe and the inferior parietal lobe were consistently demonstrated when word retrieval was contrasted with a rest state. Contrasts with other single word tasks controlled out the activation in the perisylvian part of the left posterior temporal lobe, suggesting a role forthis region in lexical processing. The left inferolateral temporal cortex and the posterior part of the inferior parietal lobe were only activated by word retrieval, particularly verbs. It is proposed that these activated regions reflect access to semantic fields.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 19:53:39