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Titolo:
2-POINT DISCRIMINATION OF ITCH IN PATIENTS WITH ATOPIC-DERMATITIS ANDHEALTHY-SUBJECTS
Autore:
WAHLGREN CF; EKBLOM A;
Indirizzi:
KAROLINSKA HOSP & INST,DEPT DERMATOL,POB 120 S-17176 STOCKHOLM SWEDEN KAROLINSKA HOSP & INST,DEPT ANAESTHESIOL & INTENS CARE S-17176 STOCKHOLM SWEDEN
Titolo Testata:
Acta dermato-venereologica
fascicolo: 1, volume: 76, anno: 1996,
pagine: 48 - 51
SICI:
0001-5555(1996)76:1<48:2DOIIP>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKIN; NEUROPEPTIDES; HISTAMINE;
Keywords:
HISTAMINE; PRURITUS; SENSORY PERCEPTION; SPATIAL SUMMATION; TACTILE DISCRIMINATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
C.F. Wahlgren e A. Ekblom, "2-POINT DISCRIMINATION OF ITCH IN PATIENTS WITH ATOPIC-DERMATITIS ANDHEALTHY-SUBJECTS", Acta dermato-venereologica, 76(1), 1996, pp. 48-51

Abstract

The ability to perceive two pruritic stimuli as separate depending onthe distance between them (two-point discrimination of itch) was determined in a single-blind study of 20 patients with atopic dermatitis and 20 healthy subjects, Itch was induced with pairs of histamine injections (0.1 mu g each) given on the upper arm, either along its axis (longitudinally within a dermatome) or at right angles to it (transversally involving more than one dermatome), The interinjection distances were varied in 3-cm steps until the shortest distance at which the two itching stimuli could be perceived as separate was found, Pairs consisting of one injection of histamine (0.1 mu g) and one of saline servedas controls. The two-point discrimination of itch was significantly better in the atopic dermatitis patients than in the healthy controls, both longitudinally (atopic dermatitis: median 12 cm, range 3-21 cm; healthy controls: 15 cm, range 9-21; p < 0.01) and transversally (atopic dermatitis: median 6 cm, range 3-18; healthy controls: 12 cm, range 6-21; p < 0.001). The two-point discrimination of itch did not correlate with the subject's age, two-point discrimination of touch, or, for the atopic dermatitis patients, with their eczema scores or serum IgE levels. The quality, intensity or spatial summation of itch did not differ significantly between the two groups of subjects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 09:27:00