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Titolo:
ADVANTAGES AND RISKS OF PANCREATIC TRANSP LANTATION IN 26 TYPE-I DIABETIC-PATIENTS
Autore:
KESSLER L; BOUDJEMA K; WOLF P; REVILLE P; PINGET M;
Indirizzi:
HOP UNIV STRASBOURG,SERV ENDOCRINOL MALAD NUTR,1 PL HOP F-67091 STRASBOURG FRANCE
Titolo Testata:
La Revue de medecine interne
fascicolo: 2, volume: 17, anno: 1996,
pagine: 117 - 124
SICI:
0248-8663(1996)17:2<117:AAROPT>2.0.ZU;2-L
Fonte:
ISI
Lingua:
FRE
Soggetto:
SINGLE INSTITUTION; KIDNEY; METABOLISM;
Keywords:
TYPE I DIABETES; PANCREAS-KIDNEY TRANSPLANTATION; QUALITY OF LIFE; UROLOGIC COMPLICATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
L. Kessler et al., "ADVANTAGES AND RISKS OF PANCREATIC TRANSP LANTATION IN 26 TYPE-I DIABETIC-PATIENTS", La Revue de medecine interne, 17(2), 1996, pp. 117-124

Abstract

From November 1990 to March 1995, 26 simultaneous pancreas-kidney (SPK) transplants were carried out. The recipients were uremic type I diabetic patients. After the first year of transplantation patient survival was 96% and pancreas and kidney survival was 69% and 84%, respectively. The pancreas transplant failure was due to veinous thrombosis (two cases), and to graft rejection (71%). The most common urologic complications of bladder drainage were urethritis (61%), bicarbonate loss (42%) and urinary tract infections (100%). Fasting blood glucose (0.91 /- 0.1 g/L), hemoglobin A1C (5,3 +/- 0.4%) and lipidic profile were found to be normal among diabetic recipients whose grafts had been functioning for 1 year. The insulin secretion of type I diabetic patients with SPK transplants (n = 13), and six non diabetic patients with kidney transplants was assessed by oral glucose tolerance tests. Only the patients with SPK transplants presented late hyperinsulinemia at 120 minutes. The quality of life for bath type I diabetic patients after SPK transplants and diabetics treated by insulinotherapy (n = 6), was studied. After transplantation, the quality of life improved only because of insulin independence. In spite of chirugical and urologic complications pancreas transplatation in type I diabetic patients improves both metabolic control and quality of life.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:24:59