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Titolo:
ANALYSIS OF MICROVASCULAR INTEGRITY, CONTRACTILE RESERVE, AND MYOCARDIAL VIABILITY AFTER ACUTE MYOCARDIAL-INFARCTION BY DOBUTAMINE ECHOCARDIOGRAPHY AND MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY
Autore:
ILICETO S; GALIUTO L; MARCHESE A; CAVALLARI D; COLONNA P; BIASCO G; RIZZON P;
Indirizzi:
UNIV CAGLIARI,INST CARDIOL,VIA SAN GIORGIO 12 CAGLIARI ITALY UNIV BARI,INST CARDIOL BARI ITALY
Titolo Testata:
The American journal of cardiology
fascicolo: 7, volume: 77, anno: 1996,
pagine: 441 - 445
SICI:
0002-9149(1996)77:7<441:AOMICR>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
TWO-DIMENSIONAL ECHOCARDIOGRAPHY; POSITRON EMISSION TOMOGRAPHY; LEFT-VENTRICULAR FUNCTION; COLLATERAL BLOOD-FLOW; NO-REFLOW PHENOMENON; LOW-DOSE DOBUTAMINE; CORONARY REVASCULARIZATION; HIBERNATING MYOCARDIUM; THROMBOLYTIC THERAPY; PERFUSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
S. Iliceto et al., "ANALYSIS OF MICROVASCULAR INTEGRITY, CONTRACTILE RESERVE, AND MYOCARDIAL VIABILITY AFTER ACUTE MYOCARDIAL-INFARCTION BY DOBUTAMINE ECHOCARDIOGRAPHY AND MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY", The American journal of cardiology, 77(7), 1996, pp. 441-445

Abstract

The purpose of this study was to evaluate, in postinfarction dysfunctioning myocardium, the relative potential of myocardial contrast and low-dose dobutamine echocardiography in detecting myocardial viability,and the relation between microvascular integrity, contractile reserve, and functional recovery at follow-vp. Twenty-four patients with recent myocardial infarction were studied before hospital discharge with low-dose dobutamine and myocardial contrast echocardiography. In the dysfunctioning infarct area, wall motion score index was calculated at baseline, during low-dose dobutamine, and at 3-month follow-up. Revascularization of the infarct-related artery was performed if clinically indicated. Eighteen patients (group A) had myocardial enhancement of the dysfunctioning infarct area at myocardial contrast echocardiography of >50%, whereas the remaining patients (group B) had an increase of less than or equal to 50%. Wall motion score index was similar at baseline in groups A and B (2.6 +/- 0.4 and 2.8 +/- 0.2; p = NS), but it improved during low-dose dobutamine and at follow-vp only in group A (1.9 +/- 0.9 and 1.9 +/- 0.7, respectively; p <0.001 vs baseline). In group B, wall motion score index was 2.7 +/- 0.4 with low-dose dobutamineand 2.8 +/- 0.2 at follow-vp (p = NS vs rest). In identifying viable myocardial segments, myocardial contrast echo had 100% sensitivity and46% specificity, whereas low-dose dobutamine echo had 71% sensitivityand 88% specificity. Thus, microvascular integrity after acute myocardial infarction is a fundamental prerequisite for ensuring myocardial contractile reserve and regional functional recovery. Myocardial contrast and low-dose dobutamine echocardiography have different, but complementary, diagnostic characteristics in detecting myocardial viability.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 07:29:20