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Titolo:
DOPAMINE INHIBITS IN-VITRO RELEASE OF VIP AND PROLIFERATION OF VIP-IMMUNOREACTIVE PITUITARY-CELLS
Autore:
CARRETERO J; VAZQUEZ RJ; SANTOS M; CACICEDO L; RUBIO M; SANCHEZFRANCO F; VAZQUEZ R;
Indirizzi:
UNIV SALAMANCA,DEPT ANAT & HISTOL HUMANAS,FAC MED,AVDA CAMPO CHARRO S-N E-37007 SALAMANCA SPAIN HOSP RAMON Y CAJAL,SERV ENDOCRINOL E-28034 MADRID SPAIN CNIC CARLOS III,SERV ENDOCRINOL MADRID SPAIN
Titolo Testata:
Neuropeptides
fascicolo: 1, volume: 30, anno: 1996,
pagine: 81 - 86
SICI:
0143-4179(1996)30:1<81:DIIROV>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASOACTIVE-INTESTINAL-PEPTIDE; ANTERIOR-PITUITARY; PROLACTIN SECRETION; MONOCLONAL-ANTIBODIES; RAT; POLYPEPTIDE; GLAND; HYPOTHALAMUS; ESTROGEN; FEMALE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
J. Carretero et al., "DOPAMINE INHIBITS IN-VITRO RELEASE OF VIP AND PROLIFERATION OF VIP-IMMUNOREACTIVE PITUITARY-CELLS", Neuropeptides, 30(1), 1996, pp. 81-86

Abstract

A double immunohistochemical study for VIP and proliferating cell nuclear antigen (PCNA) was carried out on monolayer cultures from adult male rats pituitary glands treated with dopamine (ranging from 10(-9) to 10(-5) M), in order to establish whether or not dopamine is involvedin the regulation of the proliferation rate of pituitary VIP-immunoreactive cells. For all doses of dopamine assayed, the release of VIP tothe culture medium, the numerical density of VIP-immunoreactive cellsand the percentages of VIP- and PCNA-immunoreactive cells decreased significantly after dopamine treatment. These results suggest that dopamine could be a physiological inhibitor involved in the modulation of pituitary VIP proliferation rate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 13:49:40