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Titolo:
MARKERS OF T-CELL DIFFERENTIATION AND MATURATION IN C57BL 6 AND BALB/C MICE AND IN THE CALF - A COMPARATIVE-STUDY/
Autore:
BARJA P; FREIRE M;
Indirizzi:
UNIV SANTIAGO,FAC BIOL,DEPT BIOQUIM & BIOL MOLEC,15706 CAMPUS UNIV SANTIAGO SPAIN
Titolo Testata:
Comparative biochemistry and physiology. B. Comparative biochemistry
fascicolo: 2, volume: 110, anno: 1995,
pagine: 349 - 355
SICI:
0305-0491(1995)110:2<349:MOTDAM>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW CELLS; ADENOSINE-DEAMINASE; THYMOCYTE SUBPOPULATIONS; MOUSE THYMOCYTES; LYMPHOCYTES-T; PURINE METABOLISM; LYMPHOID ORGANS; SERINE ESTERASE; THY-1; RAT;
Keywords:
T-LYMPHOCYTES; C57BL/6; BALB/C; CALF; T-CELL MATURATION; THY 1.2 ANTIGEN; MATURATION-RELATED ENZYMES; ADENOSINE DEAMINASE; SERINE-ESTERASE; N-ACETYL-BETA-D-GLUCOSAMINIDASE; BETA-GLUCURONIDASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
P. Barja e M. Freire, "MARKERS OF T-CELL DIFFERENTIATION AND MATURATION IN C57BL 6 AND BALB/C MICE AND IN THE CALF - A COMPARATIVE-STUDY/", Comparative biochemistry and physiology. B. Comparative biochemistry, 110(2), 1995, pp. 349-355

Abstract

No significant differences were found between C57BL/6 and BALB/c micein the levels of Thy 1.2 antigen (a T-cell marker) or the activities of the T-cell maturation-related enzymes adenosine deaminase (ADA, EC 3.5.4.4), serine-esterase (SE, EC 3.4.21), N-acetyl-beta-D-glucosaminidase (NABG, EC 3.2.1.30) and beta-glucuronidase (BG, EC 3.1.1.1), in either unfractionated lymphoid cells or T-lymphocyte-enriched fractions. ADA, SE, NABG and BG activities were much higher (P < 0.01) in the calf than in the corresponding populations in mice, However, the distributions of these activities among thymocyte subpopulations were very similar in mice and the calf, These results provide indirect evidence to suggest that the course of T-cell maturation is similar in mice and the calf.

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Documento generato il 14/07/20 alle ore 03:45:30