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Titolo:
A MODIFIED LIQUID DIET OF CHRONIC ETHANOL ADMINISTRATION - VALIDATIONBY ETHANOL WITHDRAWAL SYNDROME IN RATS
Autore:
UZBAY IT; KAYAALP SO;
Indirizzi:
GULHANE MIL MED ACAD,FAC MED,DEPT PHARMACOL ETLIK 06018 TURKEY HACETTEPE UNIV,FAC MED ANKARA 06100 TURKEY
Titolo Testata:
Pharmacological research
fascicolo: 1, volume: 31, anno: 1995,
pagine: 37 - 42
SICI:
1043-6618(1995)31:1<37:AMLDOC>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
VITAMIN-A DEPLETION; BENZODIAZEPINE ANTAGONIST; AUDIOGENIC-SEIZURES; ALCOHOL-WITHDRAWAL; INCREASED ANXIETY; CONSUMPTION; NITRENDIPINE; DEPENDENCE; FLUMAZENIL; DECREASE;
Keywords:
ETHANOL; LIQUID DIET; ETHANOL DEPENDENCE; ETHANOL WITHDRAWAL SYNDROME; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
I.T. Uzbay e S.O. Kayaalp, "A MODIFIED LIQUID DIET OF CHRONIC ETHANOL ADMINISTRATION - VALIDATIONBY ETHANOL WITHDRAWAL SYNDROME IN RATS", Pharmacological research, 31(1), 1995, pp. 37-42

Abstract

The validity of a modified liquid diet prepared from cow's milk, 7.2%ethanol, vitamin A and sucrose mixture has been investigated for chronic ethanol administration in rats. The rats fed by the modified liquid diet lost 3.8% of their body weight along 20 days. The mean ethanol consumption was in the range of 12.6 to 17.6 g kg(-1) day(-1). The blood ethanol level just before the withdrawal of ethanol was found to be301.38+/-36.68 mg dl(-1) A severe ethanol withdrawal syndrome was observed after 20-day exposure to ethanol in the modified liquid diet. The results suggest that the modified liquid diet can be used satisfactorily for chronic ethanol administration in rats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 15:46:34