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Titolo:
PHYSIOLOGICAL MODIFICATIONS OF BLOOD-VISCOSITY AND RED-BLOOD-CELL AGGREGATION DURING LABOR AND DELIVERY
Autore:
BRUN JF; BOULOT P; MICALLEF JP; VIALA JL; ORSETTI A;
Indirizzi:
HOP LAPEYRONIE,SERV EXPLORAT PHYSIOL HORMONES & METABOL F-34295 MONTPELLIER 5 FRANCE FAC MED MONTPELLIER,INST BIOL,PHYSIOL LAB 2 MONTPELLIER FRANCE HOP ARNAUD VILLENEUVE,SERV GYNECOL & OBSTET F-34295 MONTPELLIER 5 FRANCE INSERM,U103 F-34000 MONTPELLIER FRANCE
Titolo Testata:
Clinical hemorheology
fascicolo: 1, volume: 15, anno: 1995,
pagine: 13 - 24
SICI:
0271-5198(1995)15:1<13:PMOBAR>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ERYTHROCYTE DEFORMABILITY; NORMAL-PREGNANCY; FILTERABILITY; FILTRATION;
Keywords:
LABOR; DELIVERY; PREGNANCY; RHEOLOGY; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE AGGREGATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Brun et al., "PHYSIOLOGICAL MODIFICATIONS OF BLOOD-VISCOSITY AND RED-BLOOD-CELL AGGREGATION DURING LABOR AND DELIVERY", Clinical hemorheology, 15(1), 1995, pp. 13-24

Abstract

Since most stresses are known to modify blood theology, we studied hemorheological parameters during labor and delivery, which Are highly stressful physiological events. In 80 pregnant women we measured blood viscosity, plasma viscosity and red blood cell (RBC) aggregation during labor (before and after 4 cm dilatation), during; delivery, and during delivery of the placenta. Blood viscosity at both native and corrected hematocrit increases (p<0.001) with a peak during delivery followed by a rapid normalization during delivery of the placenta (p<0.01). Hematocrit and plasma viscosity do not change during labor and delivery, but decrease during delivery of the placenta. RBC aggregation (physiologically increased during late pregnancy) acutely returns to normal during delivery (p<0.01). The transient increase iri viscosity during delivery is explained by an increase in RBC rigidity as measured by Dintenfass' 'Tk' (p(0.01) and a similar (nonsignificant) tendency to decrease RBC filterability measured by the hemorheometre. Thus, delivery is associated with a transient hyperviscosity syndrome which is mainlydue to a decrease in RBC flexibility.

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Documento generato il 01/12/20 alle ore 16:43:24