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Titolo:
MOLECULAR-BASIS OF IMMUNE EVASION STRATEGIES BY ADENOVIRUSES
Autore:
HAYDER H; MULLBACHER A;
Indirizzi:
AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DIV CELL BIOL & IMMUNOL,POB 334 CANBERRA ACT 2601 AUSTRALIA AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DIV CELL BIOL & IMMUNOL CANBERRA ACT 2601 AUSTRALIA
Titolo Testata:
Immunology and cell biology
fascicolo: 6, volume: 74, anno: 1996,
pagine: 504 - 512
SICI:
0818-9641(1996)74:6<504:MOIESB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-NECROSIS-FACTOR; EPIDERMAL GROWTH-FACTOR; CLASS-I ANTIGENS; HIGHLY ONCOGENIC ADENOVIRUS-12; CELL-SURFACE EXPRESSION; TOXIC LYMPHOCYTES-T; BCL-2 HOMOLOG BAK; E3 GENE-PRODUCTS; NF-KAPPA-B; E3/19K PROTEIN;
Keywords:
ADENOVIRUS; HOST DEFENSE; IMMUNE EVASION; VIRAL PATHOGENESIS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
137
Recensione:
Indirizzi per estratti:
Citazione:
H. Hayder e A. Mullbacher, "MOLECULAR-BASIS OF IMMUNE EVASION STRATEGIES BY ADENOVIRUSES", Immunology and cell biology, 74(6), 1996, pp. 504-512

Abstract

Human adenoviruses have provided valuable insights into virus-host interactions at the clinical and experimental levels. In addition to themedical importance of adenoviruses in acute infections and the ability of the virus to persist in the host, adenovirus-based recombinants are being developed as potential vaccine vectors. It is now clear that adenoviruses employ various strategies to modulate the innate and the adaptive host immune defences. Adenovirus genome-coded products that interact with the immune response of the host have been identified, andto a large extent the molecular mechanisms of their functions have been revealed. Such knowledge will no doubt influence our approach to the areas of viral pathogenesis, vaccine development and immune modulation for disease management.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 09:45:47