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Titolo:
RHODOCOCCUS-EQUI INFECTION IN HIV-POSITIVE SUBJECTS - A RETROSPECTIVEANALYSIS OF 24 CASES
Autore:
ARLOTTI M; ZOBOLI G; MOSCATELLI GL; MAGNANI G; MASERATI R; BORGHI V; ANDREONI M; LIBANORE M; BONAZZI L; PISCINA A; CIAMMARUGHI R;
Indirizzi:
OSPED INFERMI,DIV MALATTIE INFETT,VIALE SETTEMBRINI 2 I-47037 RIMINI ITALY PARMA HOSP PARMA ITALY UNIV PAVIA,DEPT INFECT DIS I-27100 PAVIA ITALY UNIV MODENA I-41100 MODENA ITALY BIELLA HOSP,DIV INFECT DIS BIELLA ITALY FERRARA HOSP FERRARA ITALY OSPED REGGIO EMILIA REGGIO EMILIA ITALY RIMINI HOSP,DIV INFECT DIS RIMINI ITALY
Titolo Testata:
Scandinavian journal of infectious diseases
fascicolo: 5, volume: 28, anno: 1996,
pagine: 463 - 467
SICI:
0036-5548(1996)28:5<463:RIIHS->2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNE-DEFICIENCY SYNDROME; PULMONARY INFECTION; 17-KILODALTON ANTIGENS; OPPORTUNISTIC PATHOGEN; CORYNEBACTERIUM-EQUI; PATIENT; AIDS; PNEUMONIA; ABSCESS; SUSCEPTIBILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
M. Arlotti et al., "RHODOCOCCUS-EQUI INFECTION IN HIV-POSITIVE SUBJECTS - A RETROSPECTIVEANALYSIS OF 24 CASES", Scandinavian journal of infectious diseases, 28(5), 1996, pp. 463-467

Abstract

Rhodococcus equi causes a rare infection in immunocompromised hosts. We describe 24 cases of infection in patients with AIDS-related complex (ARC)/acquired immunodeficiency syndrome (AIDS). Pneumonia was always the first manifestation of R. equi infection, but extrapulmonary involvement was also observed. The main sources of bacteria were sputum, bronchial washings and blood. The strains isolated were mainly susceptible to erythromycin, vancomycin, teicoplanin, rifampicin, imipenem and aminoglycosides. Initial treatment should involve an intravenously administered antibiotic combination therapy including imipenem or vancomycin or teicoplanin, followed by orally administered maintenance combination therapy. Drug combinations should be investigated for serum bactericidal activity in vitro. Surgery does not increase survival time and should only be performed in cases that do not respond to antibiotic treatment. Presumptive risks of infection (contact with horses or farm dust, or cohabiting with people affected by R. equi infection) werepresent in more than 50% of patients. This finding, and the frequencyof bacteria in the sputum, are not sufficient proof of transmission between humans, but do suggest the need for respiratory isolation of patients affected by R. equi pneumonia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 00:05:26