Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SEROTONIN AND AUTISM - BIOCHEMICAL AND MOLECULAR-BIOLOGY FEATURES
Autore:
HERAULT J; PETIT E; MARTINEAU J; CHERPI C; PERROT A; BARTHELEMY C; LELORD G; MUH JP;
Indirizzi:
CHU BRETONNEAU,INSERM,U316,LAB BIOCHIM & BIOL MOL,2 BD TONNELLE F-37044 TOURS FRANCE CHU BRETONNEAU,INSERM,U316,SERV UNIV EXPLORAT FONCT & NEUROPHYSIOL PEDOPSYCH F-37044 TOURS FRANCE CHU BRETONNEAU,INSERM,U316,SERV UNIV PEDOPSYCHIAT F-37044 TOURS FRANCE
Titolo Testata:
Psychiatry research
fascicolo: 1, volume: 65, anno: 1996,
pagine: 33 - 43
SICI:
0165-1781(1996)65:1<33:SAA-BA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
WHOLE-BLOOD SEROTONIN; PLATELET SEROTONIN; INFANTILE-AUTISM; FENFLURAMINE TREATMENT; 1ST-DEGREE RELATIVES; TUBEROUS SCLEROSIS; TOURETTE SYNDROME; CHILDREN; DISORDERS; SYMPTOMS;
Keywords:
GENETICS; 5-HYDROXYTRYPTAMINE(2A) RECEPTOR; 5-HYDROXYINDOLEACETIC ACID; CHILD PSYCHIATRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
65
Recensione:
Indirizzi per estratti:
Citazione:
J. Herault et al., "SEROTONIN AND AUTISM - BIOCHEMICAL AND MOLECULAR-BIOLOGY FEATURES", Psychiatry research, 65(1), 1996, pp. 33-43

Abstract

Whole blood and urinary levels of serotonin (5-hydroxytryptamine; 5-HT) and the derivative urinary 5-hydroxyindoleacetic acid (5-HIAA) weremeasured in normal and autistic subjects. An association was tested between autism and a marker coding for the 5-HT2A serotonergic receptorgene. Significant group (high urinary 5-HT and low whole blood 5-HT in autism) and age effects (urinary 5-HT decrease with age) were found. Moreover, whole blood 5-HT levels were correlated with clinical state. No differences in allele and genotype frequencies for the 5-HT2A receptor marker were found in this autistic population compared with age-matched healthy students.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:54:34