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Titolo:
EXPRESSION OF NICOTINIC ACETYLCHOLINE-RECEPTOR MESSENGER-RNA IN THE ADULT-RAT PERIPHERAL VESTIBULAR SYSTEM
Autore:
HIEL H; ELGOYHEN AB; DRESCHER DG; MORLEY BJ;
Indirizzi:
BOYS TOWN NATL RES HOSP,NEUROCHEM LAB,555 N 30TH ST OMAHA NE 68131 BOYS TOWN NATL RES HOSP,NEUROCHEM LAB OMAHA NE 68131 CONSEJO NACL INVEST CIENT & TECN,INST INVEST FARMACOL RA-1113 BUENOS AIRES DF ARGENTINA WAYNE STATE UNIV,SCH MED,LAB BIOOTOL DETROIT MI 48201
Titolo Testata:
Brain research
fascicolo: 2, volume: 738, anno: 1996,
pagine: 347 - 352
SICI:
0006-8993(1996)738:2<347:EONAMI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUBUNIT MESSENGER-RNAS; GENE FAMILY; HAIR-CELLS; FROG; IMMUNOREACTIVITY; LOCALIZATION; ANTAGONISTS; AFFERENTS; ALPHA-4; MONKEY;
Keywords:
VESTIBULAR; EFFERENT; HYBRIDIZATION, IN SITU; HAIR CELL; NICOTINIC ACETYLCHOLINE RECEPTOR; SCARPAS GANGLION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
H. Hiel et al., "EXPRESSION OF NICOTINIC ACETYLCHOLINE-RECEPTOR MESSENGER-RNA IN THE ADULT-RAT PERIPHERAL VESTIBULAR SYSTEM", Brain research, 738(2), 1996, pp. 347-352

Abstract

The mRNA expression of the neuronal nicotinic acetylcholine receptor subunits was determined in adult rat vestibular end-organs and in Scarpa's ganglion (SCG) by in situ hybridization with [S-35]riboprobes. Neurons in the SCG expressed the alpha 4-7 and beta 2-3 mRNAs, but not alpha 3 or beta 4 mRNAs. Not all SCG neurons expressed every mRNA foundin SCG. The alpha 6 and beta 2-3 riboprobes labeled all neurons, but alpha 4, alpha 5, and alpha 7 mRNAs were selectively expressed in one or more subpopulations of SCG neurons. Vestibular sensory hair cells, in contrast, expressed only alpha 9 mRNA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 03:09:21