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Titolo:
REGULATORY ROLES OF CYCLIN-DEPENDENT KINASE PHOSPHORYLATION IN CELL-CYCLE CONTROL
Autore:
LEW DJ; KORNBLUTH S;
Indirizzi:
DUKE UNIV,MED CTR,DEPT MOL CANC BIOL,BOX 3686 DURHAM NC 27710
Titolo Testata:
Current opinion in cell biology
fascicolo: 6, volume: 8, anno: 1996,
pagine: 795 - 804
SICI:
0955-0674(1996)8:6<795:RROCKP>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
P80CDC25 MITOTIC INDUCER; SACCHAROMYCES-CEREVISIAE; FISSION YEAST; TYROSINE PHOSPHORYLATION; POSITIVE FEEDBACK; P34CDC2 KINASE; PROTEIN-KINASE; HUMAN WEE1; ACTIVATING KINASE; DNA-REPLICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
64
Recensione:
Indirizzi per estratti:
Citazione:
D.J. Lew e S. Kornbluth, "REGULATORY ROLES OF CYCLIN-DEPENDENT KINASE PHOSPHORYLATION IN CELL-CYCLE CONTROL", Current opinion in cell biology, 8(6), 1996, pp. 795-804

Abstract

Cyclins and cyclin-dependent kinases (Cdks) are universal regulators of cell cycle progression in eukaryotic cells. Cdk activity is controlled by phosphorylation at three conserved sites, and many of the enzymes that act on these sites have now been identified. Although the biochemistry of Cdk phosphorylation is relatively well understood, the regulatory roles of such phosphorylation are, in many cases, obscure. Recent studies have uncovered new and unexpected potential roles, and prompted re-examination of previously assumed roles, of Cdk phosphorylation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 17:15:13