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Titolo:
QUASI-SPECIES IN WILD-TYPE TULA HANTAVIRUS POPULATIONS
Autore:
PLYUSNIN A; CHENG Y; LEHVASLAIHO H; VAHERI A;
Indirizzi:
UNIV HELSINKI,HAARTMAN INST,DEPT VIROL,POB 21 FIN-00014 HELSINKI FINLAND CTR COMP SCI FIN-02101 ESPOO FINLAND
Titolo Testata:
Journal of virology
fascicolo: 12, volume: 70, anno: 1996,
pagine: 9060 - 9063
SICI:
0022-538X(1996)70:12<9060:QIWTHP>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC-VARIATION; GENOME SEGMENTS; VIRUS; RNA; SEQUENCES; STRAINS; REGION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
A. Plyusnin et al., "QUASI-SPECIES IN WILD-TYPE TULA HANTAVIRUS POPULATIONS", Journal of virology, 70(12), 1996, pp. 9060-9063

Abstract

Tula virus (TUL) is a recently detected hantavirus carried by European common voles. Reverse transcriptase PCR cloning was used to study TUL S segment/N protein quasispecies. Both the distribution and character of mutations observed in three mutant spectra indicated limited selection at the protein level. At least 8% of the mutations were neutral or well tolerated; fixation of such mutations may play a role in TUL evolution in its natural host.

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Documento generato il 24/09/20 alle ore 21:23:28