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Titolo:
EVIDENCE THAT INTERSEGMENTAL COMPETITION INFLUENCES THE SEGMENTAL DISTRIBUTION OF THE CENTRAL TERMINALS OF MUSCLE SENSORY AFFERENTS IN THE CHICKEN-EMBRYO
Autore:
EIDE AL; GLOVER JC;
Indirizzi:
UNIV OSLO,INST BASIC MED SCI,DEPT PHYSIOL,PB 1103 BLINDERN N-0317 OSLO NORWAY UNIV OSLO,INST BASIC MED SCI,DEPT PHYSIOL N-0317 OSLO NORWAY
Titolo Testata:
Developmental brain research
fascicolo: 1, volume: 97, anno: 1996,
pagine: 126 - 137
SICI:
0165-3806(1996)97:1<126:ETICIT>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRACHIAL SPINAL-CORD; PROJECTION PATTERNS; MOTOR NEURONS; HIND LIMB; CONNECTIONS; BULLFROG; RAT; ORGANIZATION; MOTONEURONS; INNERVATION;
Keywords:
SPINAL CORD; DORSAL ROOT GANGLION; LATERAL MOTOR COLUMN; IA AFFERENT; SYNAPTIC CONNECTIVITY; DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
A.L. Eide e J.C. Glover, "EVIDENCE THAT INTERSEGMENTAL COMPETITION INFLUENCES THE SEGMENTAL DISTRIBUTION OF THE CENTRAL TERMINALS OF MUSCLE SENSORY AFFERENTS IN THE CHICKEN-EMBRYO", Developmental brain research, 97(1), 1996, pp. 126-137

Abstract

The possibility that muscle sensory afferents that enter the spinal cord at different segmental levels compete for terminal space in the lateral motor column was tested by unilaterally ablating neural crest cells destined to generate dorsal root ganglia (DRGs). Newly migrating neural crest was surgically removed from several lumbosacral segments on one side of the spinal cord on day 3 of embryogenesis (d3). The resultant experimental preparations developed without DRGs on the operatedside at the segmental levels where the ablation was performed. At d18the central projection from the intact DRG immediately caudal to the operated segments was anatomically mapped with a lipophilic axonal tracer. The central projection from the same DRG on the opposite, unoperated side was mapped as a control. The density of terminals along the longitudinal axis of the lateral motor column was quantified in serial sections with an image analysis program. On both the operated and control sides, the majority of terminals were found within the segment of entry and the rostral and caudal neighboring spinal segments. However,the rostral neighboring segment received a larger proportion of terminals on the operated side compared to the control side. Thus, the absence of primary afferents entering the spinal cord at specific segmentsleads to a shift of the afferent projection to the lateral motor column from the neighboring segments towards the deafferented segments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 02:46:25