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Titolo:
OXYGEN-TENSION IN THE NORMAL AND VARICOSE -VEIN WALL
Autore:
TACCOEN A; LEBARD C; BORIE H; POULLAIN JC; ZUCCARELLI F; GERENTES I; STERN S; GUICHARD M;
Indirizzi:
IMMEUBLE STRASBOURG,LABS NEGMA,AVE EUROPE F-78117 TOUSSUS LE NOBLE FRANCE
Titolo Testata:
Journal des maladies vasculaires
, volume: 21, anno: 1996, supplemento:, C
pagine: 259 - 265
SICI:
0398-0499(1996)21:<259:OITNAV>2.0.ZU;2-V
Fonte:
ISI
Lingua:
FRE
Soggetto:
SMOOTH-MUSCLE CELLS; ARTERIAL-WALL; VASA VASORUM; NECK TUMORS; HYPOXIA; PATHOGENESIS; HYPERTENSION; ENDOTHELIUM; EXPRESSION; TRANSPORT;
Keywords:
OXYGEN TENSION; VENOUS WALL; VASA VASORUM; VARICOSE VEINS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
A. Taccoen et al., "OXYGEN-TENSION IN THE NORMAL AND VARICOSE -VEIN WALL", Journal des maladies vasculaires, 21, 1996, pp. 259-265

Abstract

Oxygen tension (PO2) was investigated in vivo in the long saphenous vein from 21 varicose patients (31 veins) during venous surgery and 7 patients with normal venous network undergoing popliteo-femoral by-pass. Measurement was achieved using computerized polarographic system Kimoc 6650 (Eppendorf, Hamburg) providing a microdriven stepwise progression of a needle probe. Oxygen tension profile was similar in both groups of patients. A slow PO2 decrease was observed from adventitia up tothe union of the middle and inner thirds of the media where values were at the lowest then followed by a marked increased in the intima andthe saphenous lumen. Oxygenation of the two external thirds of the venous wall was provided by vasa vasorum. The average minimum values in the media was significantly reduced in varicose veins compared to no-varicose veins (7,9 mmHg versus 13,4 mmHg; p < 0,05). These results indicated the key role of vasa vasorum flux in the long saphenous vein nutrition and suggest a primary or secondary deficiency in oxygen supplyin varicose veins.

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Documento generato il 01/12/20 alle ore 07:25:31