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Titolo:
ANALYSIS OF NUCLEAR-LOCALIZATION OF LAMININ-BINDING PROTEIN-PRECURSORP40 (LBP P40)/
Autore:
SATO M; KINOSHITA K; KANEDA Y; SAEKI Y; IWAMATSU A; TANAKA K; KANEDA Y;
Indirizzi:
OSAKA UNIV,INST MOL & CELLULAR BIOL,1-3 YAMADA OKA SUITA OSAKA 565 JAPAN OSAKA UNIV,INST MOL & CELLULAR BIOL SUITA OSAKA 565 JAPAN KIRIN BREWERY CO LTD,CENT LABS KEY TECHNOL,KANAZAWA KU YOKOHAMA KANAGAWA 236 JAPAN
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 3, volume: 229, anno: 1996,
pagine: 896 - 901
SICI:
0006-291X(1996)229:3<896:AONOLP>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA; RECEPTOR; CELLS; POLYPEPTIDE; MEMBRANES; VIRUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
M. Sato et al., "ANALYSIS OF NUCLEAR-LOCALIZATION OF LAMININ-BINDING PROTEIN-PRECURSORP40 (LBP P40)/", Biochemical and biophysical research communications, 229(3), 1996, pp. 896-901

Abstract

We isolated a monoclonal antibody M108, which recognized 40 kDa protein (40) in the cytoplasm, the perinuclear region in interphase and theperichromosomal region during mitosis. As reported previously, it wasrevealed from the immunofluorescent observation and the biochemical analyses that the nuclear p40 was associated both with the nuclear envelope and the chromatin DNA in interphase nuclei. In this report, we isolated the p40 from cytoplasmic particles, and identified it by extensive microsequencing as LBP/p40, which was considered to be a precursorof laminin binding protein p67 (LBP/p67). Epitope-tagged LBP/p40 was expressed in cultured cells, and the protein was localized in the nucleus as well as in the cytoplasm. Further analysis showed that the nuclear LBP/p40 was tightly associated with the nuclear structures. (C) 1996 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 02:59:50